Abstract
Angiomatoid fibrous histiocytoma (AFH) is a soft-tissue tumor of low-grade malignancy and uncommon metastatic behavior. In this study, we describe the clinical findings of a metastatic case of AFH in the pelvis. In addition, we characterize 16 patients in the literature with AFH who metastasized over the last 4 decades. The time of appearance of metastases varied substantially and was reported 5 months to 16 years after primary tumor resection. Nine patients metastasized to lymph nodes. Excision of metastatic lymph nodes was usually curative. Pulmonary metastases were associated with fatal outcome. Long-term monitoring should be considered in patients with AFH.
Original language | English (US) |
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Pages (from-to) | e268-e271 |
Journal | Journal of Pediatric Hematology/Oncology |
Volume | 37 |
Issue number | 4 |
DOIs | |
State | Published - Dec 1 2015 |
Keywords
- angiomatoid fibrous histiocytoma
- low grade malignancy
- metastasis
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Hematology
- Oncology