Chemotherapy for skull base cancers

Eduardo M. Diaz, Merrill S. Kies

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

The rarities of skull base cancers and locally aggressive growth patterns have prevented systematic investigation of chemotherapy and promoted the continuation of traditional surgical and postoperative radiotherapy treatment approaches. Convincing data have been generated showing the superiority of chemotherapy and radiation over radiation alone in the treatment of squamous cancers of the nasopharynx and other head and neck sites. The role of chemotherapy is being investigated for patients with locally advanced paranasal sinus tumors, undifferentiated carcinomas, and poorly differentiated skull-base neuroendocrine tumors including small cell carcinoma. Although limited, the available data favor integration of systemic chemotherapy into combined modality treatment regimens.

Original languageEnglish (US)
Pages (from-to)1079-1085
Number of pages7
JournalOtolaryngologic Clinics of North America
Volume34
Issue number6
DOIs
StatePublished - Jan 1 2001

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Skull Base
Drug Therapy
Neoplasms
Radiation
Nasopharyngeal Neoplasms
Small Cell Carcinoma
Neuroendocrine Tumors
Paranasal Sinuses
Neck
Radiotherapy
Therapeutics
Head
Carcinoma
Growth

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Chemotherapy for skull base cancers. / Diaz, Eduardo M.; Kies, Merrill S.

In: Otolaryngologic Clinics of North America, Vol. 34, No. 6, 01.01.2001, p. 1079-1085.

Research output: Contribution to journalArticle

Diaz, Eduardo M. ; Kies, Merrill S. / Chemotherapy for skull base cancers. In: Otolaryngologic Clinics of North America. 2001 ; Vol. 34, No. 6. pp. 1079-1085.
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