TY - JOUR
T1 - Chimpanzee histology and functional brain imaging show that the paracingulate sulcus is not human-specific
AU - Amiez, Céline
AU - Sallet, Jérôme
AU - Novek, Jennifer
AU - Hadj-Bouziane, Fadila
AU - Giacometti, Camille
AU - Andersson, Jesper
AU - Hopkins, William D.
AU - Petrides, Michael
N1 - Funding Information:
This work was supported by the Human Frontier Science Program (RGP0044/2014). C.A. received funding from the French National Research Agency (ANR-18-CE37-0012-01). J.S. was supported by a Sir Henry Dale Wellcome Trust Fellowship (105651/Z/14/Z) and IDEXLYON “IMPULSION” 2020 grant (IDEX/IMP/2020/14). The Wellcome Centre for Integrative Neuroimaging is supported by core funding from the Wellcome Trust (203139/Z/ 16/Z). C.A. and J.S. were also supported by Laboratoire d’excellence (LabEx) CORTEX ANR-11-LABX-0042 of Université de Lyon. W.D.H. is supported by NIH grants NS-042867, NS-073134, and NS-092988. M.P. was supported by the Canadian Institutes of Health Research (CIHR) Foundation grant FDN-143212. C.A. is employed by the Centre National de la Recherche Scientifique. We thank Sarah Lefebvre, Kristina Drudik, and Ilana Ruth Leppert for technical assistance in histology and scanning the tissue in the MRI. We also thank Franck Lamberton for help with analysis of rs-fMRI data obtained in chimpanzee.
PY - 2021/12
Y1 - 2021/12
N2 - The paracingulate sulcus -PCGS- has been considered for a long time to be specific to the human brain. Its presence/absence has been discussed in relation to interindividual variability of personality traits and cognitive abilities. Recently, a putative PCGS has been observed in chimpanzee brains. To demonstrate that this newly discovered sulcus is the homologue of the PCGS in the human brain, we analyzed cytoarchitectonic and resting-state functional magnetic resonance imaging data in chimpanzee brains which did or did not display a PCGS. The results show that the organization of the mid-cingulate cortex of the chimpanzee brain is comparable to that of the human brain, both cytoarchitectonically and in terms of functional connectivity with the lateral frontal cortex. These results demonstrate that the PCGS is not human-specific but is a shared feature of the primate brain since at least the last common ancestor to humans and great apes ~6 mya.
AB - The paracingulate sulcus -PCGS- has been considered for a long time to be specific to the human brain. Its presence/absence has been discussed in relation to interindividual variability of personality traits and cognitive abilities. Recently, a putative PCGS has been observed in chimpanzee brains. To demonstrate that this newly discovered sulcus is the homologue of the PCGS in the human brain, we analyzed cytoarchitectonic and resting-state functional magnetic resonance imaging data in chimpanzee brains which did or did not display a PCGS. The results show that the organization of the mid-cingulate cortex of the chimpanzee brain is comparable to that of the human brain, both cytoarchitectonically and in terms of functional connectivity with the lateral frontal cortex. These results demonstrate that the PCGS is not human-specific but is a shared feature of the primate brain since at least the last common ancestor to humans and great apes ~6 mya.
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U2 - 10.1038/s42003-020-01571-3
DO - 10.1038/s42003-020-01571-3
M3 - Article
C2 - 33420330
AN - SCOPUS:85098937588
VL - 4
JO - Communications Biology
JF - Communications Biology
SN - 2399-3642
IS - 1
M1 - 54
ER -