@inbook{9abb4dd37ad44b47a183ccee1ef5835f,
title = "Chitosan nanoparticles for miRNA delivery",
abstract = "RNA interference techniques represent a promising strategy for therapeutic applications. In addition to small interfering RNA-based approaches, which have been widely studied and translated into clinical investigations, microRNA-based approaches are attractive owing to their “one hit, multiple targets” concept. To overcome challenges with in vivo delivery of microRNAs related to stability, cellular uptake, and specific delivery, our group has developed and characterized chitosan nanoparticles for nucleotide delivery. This platform allows for robust target modulation and antitumor activity following intravenous administration.",
keywords = "Chitosan nanoparticles, Prostate cancer, RNA interference, miR-34a, microRNA delivery",
author = "Merve Denizli and Burcu Aslan and Mangala, {Lingegowda S.} and Dahai Jiang and Cristian Rodriguez-Aguayo and Gabriel Lopez-Berestein and Sood, {Anil K.}",
note = "Publisher Copyright: {\textcopyright} 2017, Springer Science+Business Media LLC.",
year = "2017",
doi = "10.1007/978-1-4939-7138-1_14",
language = "English (US)",
series = "Methods in Molecular Biology",
publisher = "Humana Press Inc.",
pages = "219--230",
booktitle = "Methods in Molecular Biology",
}