Cholecystectomy for prevention of recurrence after endoscopic clearance of bile duct stones in Korea

Myung Eun Song, Moon Jae Chung, Dong Jun Lee, Tak Geun Oh, Jeong Youp Park, Seungmin Bang, Seung Woo Park, Si Young Song, Jae Bock Chung

    Research output: Contribution to journalArticle

    8 Scopus citations

    Abstract

    Purpose: Cholecystectomy in patients with an intact gallbladder after endoscopic removal of stones from the common bile duct (CBD) remains controversial. We conducted a case-control study to determine the risk of recurrent CBD stones and the benefit of cholecystectomy for prevention of recurrence after endoscopic removal of stones from the CBD in Korean patients. Materials and Methods: A total of 317 patients who underwent endoscopic CBD stone extraction between 2006 and 2012 were included. Possible risk factors for the recurrence of CBD stones including previous cholecystectomy history, bile duct diameter, stone size, number of stones, stone composition, and the presence of a periampullary diverticulum were analyzed. Results: The mean duration of follow-up after CBD stone extraction was 25.4±22.0 months. A CBD diameter of 15 mm or larger [odds ratio (OR), 1.930; 95% confidence interval (CI), 1.098 to 3.391; p=0.022] and the presence of a periampullary diverticulum (OR, 1.859; 95% CI, 1.014 to 3.408; p=0.045) were independent predictive factors for CBD stone recurrence. Seventeen patients (26.6%) in the recurrence group underwent elective cholecystectomy soon after endoscopic extraction of CBD stones, compared to 88 (34.8%) in the non-recurrence group; the difference was not statistically significant (p=0.212). Conclusion: A CBD diameter of 15 mm or larger and the presence of a periampullary diverticulum were found to be potential predictive factors for recurrence after endoscopic extraction of CBD stones. Elective cholecystectomy after clearance of CBD stones did not reduce the incidence of recurrent CBD stones in Korean patients.

    Original languageEnglish (US)
    Pages (from-to)132-137
    Number of pages6
    JournalYonsei medical journal
    Volume57
    Issue number1
    DOIs
    StatePublished - Jan 2016

      Fingerprint

    Keywords

    • Cholecystectomy
    • Common bile duct
    • Gallstones
    • Recurrence

    ASJC Scopus subject areas

    • Medicine(all)

    Cite this

    Song, M. E., Chung, M. J., Lee, D. J., Oh, T. G., Park, J. Y., Bang, S., Park, S. W., Song, S. Y., & Chung, J. B. (2016). Cholecystectomy for prevention of recurrence after endoscopic clearance of bile duct stones in Korea. Yonsei medical journal, 57(1), 132-137. https://doi.org/10.3349/ymj.2016.57.1.132