Cholecystitis Related to Immune Checkpoint Inhibitor Therapy

Malek Shatila; Krishnavathana Varatharajalu; Gottumukkala Subba Raju; Anusha S. Thomas; Yinghong Wang

doi:10.1007/978-3-031-83533-9_13

Cholecystitis Related to Immune Checkpoint Inhibitor Therapy

Malek Shatila
, Krishnavathana Varatharajalu
, Gottumukkala Subba Raju
, Anusha S. Thomas
, Yinghong Wang

Gastroenterology Hepatology & Nutrition

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

We described two cases of acute cholecystitis complicated with bacteremia and abscess post immune checkpoint inhibitors. All the alternative etiologies have been excluded for the cholecystitis. Both cases responded to antibiotic treatment in combination with percutaneous cholecystostomy. The role of surgery and steroid for post immunotherapy cholecystitis remains to be investigated.

Original language	English (US)
Title of host publication	Challenging Cases in Immunotherapy Related Organ Toxicities
Publisher	Springer Science+Business Media
Pages	95-101
Number of pages	7
ISBN (Electronic)	9783031835339
ISBN (Print)	9783031835322
DOIs	https://doi.org/10.1007/978-3-031-83533-9_13
State	Published - Jan 1 2025

Keywords

Adverse event
Cholecystitis
Immune checkpoint inhibitors
Toxicity

ASJC Scopus subject areas

General Medicine

Access to Document

10.1007/978-3-031-83533-9_13

Cite this

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abstract = "We described two cases of acute cholecystitis complicated with bacteremia and abscess post immune checkpoint inhibitors. All the alternative etiologies have been excluded for the cholecystitis. Both cases responded to antibiotic treatment in combination with percutaneous cholecystostomy. The role of surgery and steroid for post immunotherapy cholecystitis remains to be investigated.",

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AU - Shatila, Malek

AU - Varatharajalu, Krishnavathana

AU - Raju, Gottumukkala Subba

AU - Thomas, Anusha S.

AU - Wang, Yinghong

PY - 2025/1/1

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AB - We described two cases of acute cholecystitis complicated with bacteremia and abscess post immune checkpoint inhibitors. All the alternative etiologies have been excluded for the cholecystitis. Both cases responded to antibiotic treatment in combination with percutaneous cholecystostomy. The role of surgery and steroid for post immunotherapy cholecystitis remains to be investigated.

KW - Adverse event

KW - Cholecystitis

KW - Immune checkpoint inhibitors

KW - Toxicity

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M3 - Chapter

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BT - Challenging Cases in Immunotherapy Related Organ Toxicities

PB - Springer Science+Business Media

ER -

Cholecystitis Related to Immune Checkpoint Inhibitor Therapy

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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