Chronic tophaceous gout with severely deforming arthritis: A case report with emphasis on histopathologic considerations

P. R. Cohen; W. A. Schmidt; R. P. Rapini

Chronic tophaceous gout with severely deforming arthritis: A case report with emphasis on histopathologic considerations

P. R. Cohen
, W. A. Schmidt
, R. P. Rapini

Dermatology

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

The dramatic clinical presentation of a patient with severe deforming arthritis secondary to chronic tophaceous gout is described. Polarization microscopic examination and use of the De Galantha stain identified the dermal amorphous material as urate crystals. When the possibility of gout is entertained and a lesional biopsy specimen is examined to confirm the diagnosis, it is useful to fix the fresh tissue in absolute ethanol and process the specimen using an anhydrous technique to preserve the crystals.

Original language	English (US)
Pages (from-to)	445-451
Number of pages	7
Journal	Cutis
Volume	48
Issue number	6
State	Published - 1991

ASJC Scopus subject areas

General Medicine

Cite this

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title = "Chronic tophaceous gout with severely deforming arthritis: A case report with emphasis on histopathologic considerations",

abstract = "The dramatic clinical presentation of a patient with severe deforming arthritis secondary to chronic tophaceous gout is described. Polarization microscopic examination and use of the De Galantha stain identified the dermal amorphous material as urate crystals. When the possibility of gout is entertained and a lesional biopsy specimen is examined to confirm the diagnosis, it is useful to fix the fresh tissue in absolute ethanol and process the specimen using an anhydrous technique to preserve the crystals.",

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year = "1991",

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N2 - The dramatic clinical presentation of a patient with severe deforming arthritis secondary to chronic tophaceous gout is described. Polarization microscopic examination and use of the De Galantha stain identified the dermal amorphous material as urate crystals. When the possibility of gout is entertained and a lesional biopsy specimen is examined to confirm the diagnosis, it is useful to fix the fresh tissue in absolute ethanol and process the specimen using an anhydrous technique to preserve the crystals.

AB - The dramatic clinical presentation of a patient with severe deforming arthritis secondary to chronic tophaceous gout is described. Polarization microscopic examination and use of the De Galantha stain identified the dermal amorphous material as urate crystals. When the possibility of gout is entertained and a lesional biopsy specimen is examined to confirm the diagnosis, it is useful to fix the fresh tissue in absolute ethanol and process the specimen using an anhydrous technique to preserve the crystals.

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M3 - Article

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AN - SCOPUS:0026330939

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VL - 48

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JO - Cutis

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ER -

Chronic tophaceous gout with severely deforming arthritis: A case report with emphasis on histopathologic considerations

Abstract

ASJC Scopus subject areas

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