Clinical and Imaging Features of Head and Neck Metastasis of High-Grade Glioma: A Single-Center Case Series

Rami W. Eldaya; Diana Kaya; Michelle Williams; Susana Calle; Dawid Schellingerhout

doi:10.3174/ajnr.A8521

Clinical and Imaging Features of Head and Neck Metastasis of High-Grade Glioma: A Single-Center Case Series

Rami W. Eldaya, Diana Kaya, Michelle Williams, Susana Calle, Dawid Schellingerhout

Research output: Contribution to journal › Article › peer-review

Abstract

SUMMARY: High-grade gliomas are the most frequent primary brain tumors, yet extraneural metastasis is exceedingly rare. This is in part secondary to the relatively poor survival of these patients and likely the shielding effect of the blood-brain barrier. Given the rarity of extraneural metastasis, the pathophysiology and imaging appearance of extraneural metastasis is under-reported and poorly understood. In this case series we present 6 patients with pathology-confirmed high-grade glioma and extraneural head and neck metastasis. We highlight imaging features of metastasis on CT, MRI, and PET/CT. We also explore potential correlations and pathophysiology of high-grade glioma metastasis to the head and neck region.

Original language	English (US)
Pages (from-to)	160-165
Number of pages	6
Journal	American Journal of Neuroradiology
Volume	46
Issue number	1
DOIs	https://doi.org/10.3174/ajnr.A8521
State	Published - Jan 1 2025

Keywords

IQR ¼ interquartile range
US ¼ ultrasound

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging
Clinical Neurology

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abstract = "SUMMARY: High-grade gliomas are the most frequent primary brain tumors, yet extraneural metastasis is exceedingly rare. This is in part secondary to the relatively poor survival of these patients and likely the shielding effect of the blood-brain barrier. Given the rarity of extraneural metastasis, the pathophysiology and imaging appearance of extraneural metastasis is under-reported and poorly understood. In this case series we present 6 patients with pathology-confirmed high-grade glioma and extraneural head and neck metastasis. We highlight imaging features of metastasis on CT, MRI, and PET/CT. We also explore potential correlations and pathophysiology of high-grade glioma metastasis to the head and neck region.",

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T1 - Clinical and Imaging Features of Head and Neck Metastasis of High-Grade Glioma

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AU - Eldaya, Rami W.

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AU - Williams, Michelle

AU - Calle, Susana

AU - Schellingerhout, Dawid

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N2 - SUMMARY: High-grade gliomas are the most frequent primary brain tumors, yet extraneural metastasis is exceedingly rare. This is in part secondary to the relatively poor survival of these patients and likely the shielding effect of the blood-brain barrier. Given the rarity of extraneural metastasis, the pathophysiology and imaging appearance of extraneural metastasis is under-reported and poorly understood. In this case series we present 6 patients with pathology-confirmed high-grade glioma and extraneural head and neck metastasis. We highlight imaging features of metastasis on CT, MRI, and PET/CT. We also explore potential correlations and pathophysiology of high-grade glioma metastasis to the head and neck region.

AB - SUMMARY: High-grade gliomas are the most frequent primary brain tumors, yet extraneural metastasis is exceedingly rare. This is in part secondary to the relatively poor survival of these patients and likely the shielding effect of the blood-brain barrier. Given the rarity of extraneural metastasis, the pathophysiology and imaging appearance of extraneural metastasis is under-reported and poorly understood. In this case series we present 6 patients with pathology-confirmed high-grade glioma and extraneural head and neck metastasis. We highlight imaging features of metastasis on CT, MRI, and PET/CT. We also explore potential correlations and pathophysiology of high-grade glioma metastasis to the head and neck region.

KW - IQR ¼ interquartile range

KW - US ¼ ultrasound

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Clinical and Imaging Features of Head and Neck Metastasis of High-Grade Glioma: A Single-Center Case Series

Abstract

Keywords

ASJC Scopus subject areas

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