TY - JOUR
T1 - Clinical Trials for the Surgical Oncologist
T2 - Opportunities and Hurdles
AU - Park, Ko Un
AU - Mamounas, Eleftherios P.
AU - Katz, Matthew H.G.
AU - Unzeitig, Gary
AU - Carpizo, Darren
AU - You, Y. Nancy
AU - Francescatti, Amanda
AU - Hunt, Kelly K.
AU - Boughey, Judy C.
N1 - Publisher Copyright:
© 2020, Society of Surgical Oncology.
PY - 2020/7/1
Y1 - 2020/7/1
N2 - Advancements in clinical practice usually require level one evidence from clinical trials that directly compare new approaches to standard of care. While clinical trials have provided data to guide advances in practices across surgical oncology, all too often accrual to clinical trials is slower than anticipated, and once results are presented and published, adoption in clinical practice is slow. Why and how can surgeons be successfully involved with clinical trials? An expert panel discusses the basic infrastructure of clinical trials, investigator-initiated trials, the National Clinical Trials Network, and opportunities for surgeon involvement. Two national clinical trials, NSABP B-51/RTOG 1304 and PROSPECT N1048, are discussed to highlight the role of the surgical oncologist.
AB - Advancements in clinical practice usually require level one evidence from clinical trials that directly compare new approaches to standard of care. While clinical trials have provided data to guide advances in practices across surgical oncology, all too often accrual to clinical trials is slower than anticipated, and once results are presented and published, adoption in clinical practice is slow. Why and how can surgeons be successfully involved with clinical trials? An expert panel discusses the basic infrastructure of clinical trials, investigator-initiated trials, the National Clinical Trials Network, and opportunities for surgeon involvement. Two national clinical trials, NSABP B-51/RTOG 1304 and PROSPECT N1048, are discussed to highlight the role of the surgical oncologist.
UR - http://www.scopus.com/inward/record.url?scp=85084144470&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85084144470&partnerID=8YFLogxK
U2 - 10.1245/s10434-020-08472-z
DO - 10.1245/s10434-020-08472-z
M3 - Article
C2 - 32318946
AN - SCOPUS:85084144470
SN - 1068-9265
VL - 27
SP - 2269
EP - 2275
JO - Annals of surgical oncology
JF - Annals of surgical oncology
IS - 7
ER -