Abstract
A gene homologous to the human putative tumor suppressor gene QM, designated OSQM1, was isolated from rice (Oryza sativa L.) genomic DNA library using through homology screening. It contained 4 exons and 3 introns, encoding a protein of 219 amino acids with 46 basic amino acids, leading to a high iso-electric point of 11.02. Homology search showed that this gene existed in eukaryotes and highly conserved throughout eukaryotes, suggesting an essential role of this gene. Northern blot analysis showed that it was expressed in various rice organs, but at lower level in developing flower and callus tissue than in other vegetative organs. Its expression levels in roots and leaves were influenced by different environmental factors.
Original language | English (US) |
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Pages (from-to) | 562-566 |
Number of pages | 5 |
Journal | Acta Botanica Sinica |
Volume | 44 |
Issue number | 5 |
State | Published - 2002 |
Externally published | Yes |
Keywords
- Eukaryotes
- QM
- Tumor suppressor gene
ASJC Scopus subject areas
- Biochemistry
- General Biochemistry, Genetics and Molecular Biology
- Plant Science