TY - JOUR
T1 - Colorectal cancer in the adolescent and young adult population
AU - You, Y. Nancy
AU - Lee, Lucas D.
AU - Deschner, Benjamin W.
AU - Shibata, David
N1 - Funding Information:
Supported in part by University of Texas MD Anderson Cancer Center Core Support Grant No. P30 CA016672.
Publisher Copyright:
© 2020 by American Society of Clinical Oncology
PY - 2020
Y1 - 2020
N2 - Colorectal cancer in the young adult population is of increasing incidence and concern. Genetic predisposition and heritable syndromes contribute to this trend, but perhaps more concerning is the majority of new diagnoses that involve no traceable genetic risk factors. Prevention and early recognition, with a high suspicion in the symptomatic young adult, are critical in attenuating recent trends. Clinical management requires coordinated multidisciplinary care from diagnosis to surveillance in order to ensure appropriate management. This review provides a summary of key aspects related to colorectal cancer in adolescents and young adults, including epidemiology, biology, genetics, clinical management, and prevention.
AB - Colorectal cancer in the young adult population is of increasing incidence and concern. Genetic predisposition and heritable syndromes contribute to this trend, but perhaps more concerning is the majority of new diagnoses that involve no traceable genetic risk factors. Prevention and early recognition, with a high suspicion in the symptomatic young adult, are critical in attenuating recent trends. Clinical management requires coordinated multidisciplinary care from diagnosis to surveillance in order to ensure appropriate management. This review provides a summary of key aspects related to colorectal cancer in adolescents and young adults, including epidemiology, biology, genetics, clinical management, and prevention.
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U2 - 10.1200/JOP.19.00153
DO - 10.1200/JOP.19.00153
M3 - Article
C2 - 32039664
AN - SCOPUS:85079145070
SN - 1554-7477
VL - 16
SP - 19
EP - 27
JO - Journal of oncology practice
JF - Journal of oncology practice
IS - 1
ER -