Combination of fluorescence and reflectance spectroscopy for in vivo detection of cervical pre-cancers

Sung K. Chang, Yvette N. Mirabal, E. Neely Atkinson, Anais Malpica, Michele Follen, Rebecca Richards-Kortum

Research output: Contribution to journalConference articlepeer-review

4 Scopus citations

Abstract

The goal of this study is to identify fluorescence excitation wavelengths and reflectance source-detector separations that are significant for diagnosis of cervical pre-cancers. Measurements from fluorescence and reflectance spectroscopy were searched exhaustively using Mahalanobis distance based classification. Fluorescence excitation wavelengths at 340nm, 350 nm and 410 nm and reflectance source-detector separation of 250 μm appear significant for discriminating a pair of diagnostic classes.

Original languageEnglish (US)
Pages (from-to)2265-2266
Number of pages2
JournalAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Volume3
StatePublished - 2002
EventProceedings of the 2002 IEEE Engineering in Medicine and Biology 24th Annual Conference and the 2002 Fall Meeting of the Biomedical Engineering Society (BMES / EMBS) - Houston, TX, United States
Duration: Oct 23 2002Oct 26 2002

Keywords

  • Fluorescence
  • Pre-cancer detection
  • Reflectance
  • Spectroscopy

ASJC Scopus subject areas

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

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