Abstract
Patients with multiple myeloma often receive dexamethasone in combination with novel agent treatment. The current study compared the rate and extent of absorption of a single 20-mg dexamethasone tablet to five 4-mg tablets (total, 20 mg). Both formulations were well-tolerated and bioequivalent under fasting conditions, and dexamethasone 20-mg tablet under fed conditions demonstrated comparable total exposure to fasted conditions.
Original language | English (US) |
---|---|
Pages (from-to) | 768-773 |
Number of pages | 6 |
Journal | Clinical Lymphoma, Myeloma and Leukemia |
Volume | 20 |
Issue number | 11 |
DOIs | |
State | Published - Nov 2020 |
Keywords
- Bioavailability
- Corticosteroids
- Dexamethasone
- Myeloma
- Oral formulation
ASJC Scopus subject areas
- Hematology
- Oncology
- Cancer Research