TY - GEN
T1 - Comparison of a GATE Monte Carlo simulation predictions to the performance of a high-resolution LYSO based dedicated animal PET camera
AU - Baghaei, Hossain
AU - Zhang, Yuxuan
AU - Li, Hongdi
AU - Ramirez, Rocio A.
AU - Liu, Shitao
AU - Wang, Chao
AU - An, Shaohui
AU - Wong, Wai Hoi
N1 - Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2011
Y1 - 2011
N2 - A Monte Carlo simulation of the performance of a high-sensitivity and high-resolution small animal positron emission tomography (PET) scanner with a large axial field-of-view (AFOV) is presented and compared to the measured data. The simulated camera is based on the photomultiplier-quadrant-sharing (PQS) concept and composed of 180 blocks of 13x13 lutetium-yttrium oxyorthosilicate (LYSO) crystals with an average crystal size of 1.24 mm transaxially, 1.4 mm axially, and 9.5 mm radially. The camera has 78 detector rings with an 11.6 cm AFOV and a ring diameter of 16.6 cm. For the simulation, we used the Geant4 Application for Tomographic Emission (GATE) simulation package. We first validated GATE by comparing its predictions for spatial resolution, absolute sensitivity, and count rate with measured data obtained using an existing bismuth germanate (BGO) based dedicated animal PET scanner that had a similar AFOV and ring diameter and was also based on the PQS technique. Simulated and experimental images of the Data Spectrum Micro Deluxe phantom were also compared.
AB - A Monte Carlo simulation of the performance of a high-sensitivity and high-resolution small animal positron emission tomography (PET) scanner with a large axial field-of-view (AFOV) is presented and compared to the measured data. The simulated camera is based on the photomultiplier-quadrant-sharing (PQS) concept and composed of 180 blocks of 13x13 lutetium-yttrium oxyorthosilicate (LYSO) crystals with an average crystal size of 1.24 mm transaxially, 1.4 mm axially, and 9.5 mm radially. The camera has 78 detector rings with an 11.6 cm AFOV and a ring diameter of 16.6 cm. For the simulation, we used the Geant4 Application for Tomographic Emission (GATE) simulation package. We first validated GATE by comparing its predictions for spatial resolution, absolute sensitivity, and count rate with measured data obtained using an existing bismuth germanate (BGO) based dedicated animal PET scanner that had a similar AFOV and ring diameter and was also based on the PQS technique. Simulated and experimental images of the Data Spectrum Micro Deluxe phantom were also compared.
UR - https://www.scopus.com/pages/publications/84863344833
UR - https://www.scopus.com/pages/publications/84863344833#tab=citedBy
U2 - 10.1109/NSSMIC.2011.6152651
DO - 10.1109/NSSMIC.2011.6152651
M3 - Conference contribution
AN - SCOPUS:84863344833
SN - 9781467301183
T3 - IEEE Nuclear Science Symposium Conference Record
SP - 2388
EP - 2392
BT - 2011 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2011
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 2011 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2011
Y2 - 23 October 2011 through 29 October 2011
ER -