TY - JOUR
T1 - Contemporary Approach to Locally Advanced Oral Cavity Squamous Cell Carcinoma
AU - Yao, Christopher M.K.L.
AU - Chang, Edward I.
AU - Lai, Stephen Y.
PY - 2019/11/1
Y1 - 2019/11/1
N2 - Purpose of Review: Surgical management of locally advanced oral cavity squamous cell carcinomas (OCSCC) has long been recognized as a primary treatment modality. Technological advances have led to significant improvements in our surgical approach, from improvement in the visualization of tumors to more efficient and precise reconstruction. Here, we review the latest technological advances in surgical extirpation and reconstruction of locally advanced OCSCCs. Recent Findings: The focus of technological innovation in surgical extirpation has been on improving visualization, with the use of intraoperative ultrasound for margin delineation, intraoperative navigation, narrow-band imaging, and the use of fluorescence. Though early, these are promising steps to ensuring complete resection of the cancer. Advances in reconstruction have been centered on the incorporation of computer assisted design, manufacturing, and virtual surgical planning, allowing for more complex three-dimensional defects to be expeditiously reconstructed. Summary: As these technologies are still under development, their impact on oncologic outcomes are not yet robustly defined; however, as technology continues to advance and become more widely available, new technologies will undoubtedly become integrated into enhancing surgical precision and planning.
AB - Purpose of Review: Surgical management of locally advanced oral cavity squamous cell carcinomas (OCSCC) has long been recognized as a primary treatment modality. Technological advances have led to significant improvements in our surgical approach, from improvement in the visualization of tumors to more efficient and precise reconstruction. Here, we review the latest technological advances in surgical extirpation and reconstruction of locally advanced OCSCCs. Recent Findings: The focus of technological innovation in surgical extirpation has been on improving visualization, with the use of intraoperative ultrasound for margin delineation, intraoperative navigation, narrow-band imaging, and the use of fluorescence. Though early, these are promising steps to ensuring complete resection of the cancer. Advances in reconstruction have been centered on the incorporation of computer assisted design, manufacturing, and virtual surgical planning, allowing for more complex three-dimensional defects to be expeditiously reconstructed. Summary: As these technologies are still under development, their impact on oncologic outcomes are not yet robustly defined; however, as technology continues to advance and become more widely available, new technologies will undoubtedly become integrated into enhancing surgical precision and planning.
KW - Advanced oral cavity carcinoma
KW - Image-guided surgery
KW - Oral cavity reconstruction
KW - Technology
KW - Tumor margins
KW - Virtual surgical planning
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U2 - 10.1007/s11912-019-0845-8
DO - 10.1007/s11912-019-0845-8
M3 - Review article
C2 - 31701240
AN - SCOPUS:85074727721
SN - 1523-3790
VL - 21
JO - Current oncology reports
JF - Current oncology reports
IS - 11
M1 - 99
ER -