Abstract
Following publication of the original article [1], errors were found in Fig. 5a due to misused of images in Hep3B-SCR/EV, -shOPN/EV, and -shOPN/DNMT1. The correct figure is given below: OPN modulates the properties of CD133+/CD44 + cells through regulating DNMT1. a When CD133+/CD44 + cells with shOPN were transfected with DNMT1 from Huh7 and Hep3B cells, the ability of sphere forming was rescued compared to the shOPN group, 40X. b The expression of indicated genes down regulated in CD133+/CD44 + cells from Huh7 and Hep3B transfected with shOPN compared to the control, were reversed in part by DNMT1 transfection. c The number of spheres formed by CD133+/CD44 + cells with EV, CD133+/CD44 + cells with OPN and CD133+/CD44 + cells with OPN treated by 5 Aza, **, p < 0.01, ***, p < 0.001. d The number of spheres formed by CD133+/CD44 + cells with EV/SCR, CD133+/CD44 + cells with OPN/SCR and CD133+/CD44 + cells with OPN/shDNMT1, **, p < 0.01. e CD133+/CD44 + SCR/EV, CD133+/CD44 + shOPN/EV and CD133+/CD44 + cells shOPN/DNMT1 from Huh7 were injected subcutaneously into the mice, and recorded the time of tumor initiation, tumor weight and tumor volume, **, p < 0.01, ***, p < 0.001, NS, no significance. f IHC staining of stemness-related markers, OCT4 and Nanog in the tumor tissues derived from CD133+/CD44 + cells with SCR/EV or shOPN/EV or shOPN/DNMT1.
| Original language | English (US) |
|---|---|
| Article number | 266 |
| Journal | Journal of Experimental and Clinical Cancer Research |
| Volume | 42 |
| Issue number | 1 |
| DOIs |
|
| State | Published - Dec 2023 |
| Externally published | Yes |
ASJC Scopus subject areas
- Oncology
- Cancer Research
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Dive into the research topics of 'Correction: Osteopontin alters DNA methylation through up-regulating DNMT1 and sensitizes CD133+/CD44 + cancer stem cells to 5 azacytidine in hepatocellular carcinoma (Journal of Experimental & Clinical Cancer Research, (2018), 37, 1, (179), 10.1186/s13046-018-0832-1)'. Together they form a unique fingerprint.Cite this
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