TY - JOUR
T1 - Crystal structures of bis(L(-)prolinato-N)(trans-R,R-1,2-diaminocyclohexane)platinum(II) and bis(L(-)prolinato-N)-(cis-1,2-diaminocyclohexane)platinum(II) complexes
AU - Khokhar, Abdul R.
AU - Xu, Quanyun
AU - Al-Baker, Salaam A.
AU - Lumetta, Gregg J.
N1 - Funding Information:
This work was supported by Grant CA41581 from the National Cancer Institute to ARK. We thank Dr J. Korp for helpful discussions.
PY - 1993/1/3
Y1 - 1993/1/3
N2 - The molecular structures of the compounds bis(L(-)prolinato-N)(trans-R,R-1,2-diaminocyclohexane)platinum(II) and bis(L(-)prolinato-N)(cis-1,2-diaminocyclohexane)platinum(II) have been established by single crystal X-ray diffraction. The average plane of the cyclohexane ring of the cis-DACH is nearly perpendicular to the PtN4 plane, while the ring of the trans-R,R-DACH is nearly coplanar with PtN4. Two prolinate ligands are bound to the platinum through amino nitrogen atoms. Crystallographic details: bis(L(-)prolinato-N)(trans-R,R-1,2- diaminocyclohexane)platinum(II): space group P212121 (orthorhombic), a = 10.301(2), b = 12.364(2), c = 17.920(4) Å, Z = 4, R = 0.019; bis(L(-)prolinato-N)(cis-1,2-diaminocyclohexane)platinum(II): space group P212121 (orthorhombic), a = 11.496(5), b = 12.918(6), c = 16.527(9) Å, Z = 4, R = 0.040.
AB - The molecular structures of the compounds bis(L(-)prolinato-N)(trans-R,R-1,2-diaminocyclohexane)platinum(II) and bis(L(-)prolinato-N)(cis-1,2-diaminocyclohexane)platinum(II) have been established by single crystal X-ray diffraction. The average plane of the cyclohexane ring of the cis-DACH is nearly perpendicular to the PtN4 plane, while the ring of the trans-R,R-DACH is nearly coplanar with PtN4. Two prolinate ligands are bound to the platinum through amino nitrogen atoms. Crystallographic details: bis(L(-)prolinato-N)(trans-R,R-1,2- diaminocyclohexane)platinum(II): space group P212121 (orthorhombic), a = 10.301(2), b = 12.364(2), c = 17.920(4) Å, Z = 4, R = 0.019; bis(L(-)prolinato-N)(cis-1,2-diaminocyclohexane)platinum(II): space group P212121 (orthorhombic), a = 11.496(5), b = 12.918(6), c = 16.527(9) Å, Z = 4, R = 0.040.
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U2 - 10.1016/S0020-1693(00)82915-1
DO - 10.1016/S0020-1693(00)82915-1
M3 - Article
AN - SCOPUS:0000373509
SN - 0020-1693
VL - 203
SP - 121
EP - 125
JO - Inorganica Chimica Acta
JF - Inorganica Chimica Acta
IS - 1
ER -