CT on-line monitoring of HIFU therapy

J. W. Jenne, M. Bahner, J. Spoo, Peter Huber, R. Rastert, L. Simiantonakis, W. J. Lorenz, J. Debus

Research output: Contribution to journalConference article

30 Citations (Scopus)

Abstract

It was the aim of this study scanner evaluate the feasibility of a clinical CT scanner for temperature mapping in high intensity focused ultrasound tumor therapy. We used a 1.2 MHz ultrasound transducer for HIFU on fresh pig muscle. Image acquisition was performed with a clinical CT Scanner before, during and after HIFU. We were able to determine the spatial and temporal temperature development during HIFU application as hypodense zones in the performed images. Thermal necroses were shown as hyperdense areas in the CT images. Moreover, we were able to detect bubble formation due to vaporization during US application. Calibration showed a CT thermosensitivity of -0.43 HU/°C in pig muscle tissue.

Original languageEnglish (US)
Pages (from-to)1377-1380
Number of pages4
JournalProceedings of the IEEE Ultrasonics Symposium
Volume2
StatePublished - Dec 1 1997
EventProceedings of the 1997 IEEE Ultrasonics Symposium. Part 1 (of 2) - Toronto, Can
Duration: Oct 5 1997Oct 8 1997

Fingerprint

scanners
Muscle
therapy
swine
Ultrasonics
muscles
Bubble formation
Monitoring
Image acquisition
Vaporization
Tumors
Transducers
necrosis
Calibration
Tissue
Temperature
acquisition
transducers
bubbles
tumors

ASJC Scopus subject areas

  • Acoustics and Ultrasonics

Cite this

Jenne, J. W., Bahner, M., Spoo, J., Huber, P., Rastert, R., Simiantonakis, L., ... Debus, J. (1997). CT on-line monitoring of HIFU therapy. Proceedings of the IEEE Ultrasonics Symposium, 2, 1377-1380.

CT on-line monitoring of HIFU therapy. / Jenne, J. W.; Bahner, M.; Spoo, J.; Huber, Peter; Rastert, R.; Simiantonakis, L.; Lorenz, W. J.; Debus, J.

In: Proceedings of the IEEE Ultrasonics Symposium, Vol. 2, 01.12.1997, p. 1377-1380.

Research output: Contribution to journalConference article

Jenne, JW, Bahner, M, Spoo, J, Huber, P, Rastert, R, Simiantonakis, L, Lorenz, WJ & Debus, J 1997, 'CT on-line monitoring of HIFU therapy', Proceedings of the IEEE Ultrasonics Symposium, vol. 2, pp. 1377-1380.
Jenne JW, Bahner M, Spoo J, Huber P, Rastert R, Simiantonakis L et al. CT on-line monitoring of HIFU therapy. Proceedings of the IEEE Ultrasonics Symposium. 1997 Dec 1;2:1377-1380.
Jenne, J. W. ; Bahner, M. ; Spoo, J. ; Huber, Peter ; Rastert, R. ; Simiantonakis, L. ; Lorenz, W. J. ; Debus, J. / CT on-line monitoring of HIFU therapy. In: Proceedings of the IEEE Ultrasonics Symposium. 1997 ; Vol. 2. pp. 1377-1380.
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