Abstract
The oral cavity is the most common site of head and neck squamous cell carcinoma, a disease which results in significant morbidity and mortality worldwide. Though the primary modality of treatment for patients with oral cavity cancer remains surgical resection, many patients present with advanced disease and are thus treated using a multi-disciplinary approach. Patients with extracapsular spread of lymphatic metastasis and surgical margins that remain positive have been found to be at high risk for local-regional recurrence and death from disease, and are most often recommended to receive both postoperative radiation as well as systemic chemotherapy. The basis for this approach, as well as scientific developments that underly future trials of novels treatments for patients with high-risk oral cavity cancer are reviewed.
Original language | English (US) |
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Pages (from-to) | 1-10 |
Number of pages | 10 |
Journal | Clinical and Experimental Otorhinolaryngology |
Volume | 4 |
Issue number | 1 |
DOIs | |
State | Published - Mar 2011 |
Keywords
- Chemotherapy
- Head and neck neoplasms
- Oral cancer
- Radiotherapy
- Surgery
- Treatment
ASJC Scopus subject areas
- Surgery
- Otorhinolaryngology