Current Role of Radiation Therapy in the Management of Malignant Central Nervous System Tumors

Ahsan Farooqi, Jing Li, John de Groot, Debra Nana Yeboa

Research output: Contribution to journalReview article

Abstract

The 2016 World Health Organization classification of central nervous system (CNS) tumors underwent significant restructuring and for the first time gliomas are classified according to both molecular and histologic parameters which guides glioma management. Radiation for intermediate-risk meningiomas improves the progression-free survival from historical controls, and studies are ongoing for atypical meningiomas. For brain metastases, use of stereotactic radiosurgery for a higher number of lesions has become clinical practice. Additionally, hippocampal-sparing whole brain radiation shows promise in preserving neuro-cognitive function. This article summarizes the evolving role of radiation therapy in the management of malignant CNS neoplasms.

Original languageEnglish (US)
Pages (from-to)13-28
Number of pages16
JournalHematology/Oncology Clinics of North America
Volume34
Issue number1
DOIs
StatePublished - Feb 2020

Fingerprint

Central Nervous System Neoplasms
Meningioma
Glioma
Radiotherapy
Radiation
Radiosurgery
Brain
Cognition
Disease-Free Survival
Neoplasm Metastasis
Historically Controlled Study

Keywords

  • Brain metastases
  • Central nervous system brain tumors
  • Clinical review
  • Glioma
  • Meningioma
  • Radiation therapy

ASJC Scopus subject areas

  • Hematology
  • Oncology

Cite this

Current Role of Radiation Therapy in the Management of Malignant Central Nervous System Tumors. / Farooqi, Ahsan; Li, Jing; de Groot, John; Yeboa, Debra Nana.

In: Hematology/Oncology Clinics of North America, Vol. 34, No. 1, 02.2020, p. 13-28.

Research output: Contribution to journalReview article

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