Debulking operation for non-small cell lung cancer

W. Yilong, H. Zhifan, R. Tiehua

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Objective: To assess effectiveness arid influencing factors of debulking operation for non-small cell lung cancer. Methods: The cumulative survival and its influencing factors were analyzed and compared by the Kaplan-Meier and Cox model of SPSS for Windows in 244 patients received debulking operation and 364 received thoracotomy. Results: The 1,3,5-year cumulative survival of patients treated with debulking operation was 56.9%, 20.6%, 17.5% respectively while that received thoracotomy was 41.1%, 7.8%, 5.3%, respectively (debulking vs thoracotomy, Breslow= 27.55, P <0. 0001). Multivariate analysis showed that the debulking operation or thoracotomy (B= 0. 4600, P<0. 0001) and postoperative adjuvant therapies (B= -0. 1059, P= 0. 0216) were the most important influencing factors on the cumulative survival. Conclusion: Tumor debulking operation is an important treatment for stage I, IV non-small cell lung cancer. With postoperative adjuvant chemoradiotherapy better survival can be achieved.

Original languageEnglish (US)
Pages (from-to)442-444
Number of pages3
JournalChinese Journal of Oncology
Volume19
Issue number6
StatePublished - Dec 1 1997

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Thoracotomy
Non-Small Cell Lung Carcinoma
Survival
Adjuvant Chemoradiotherapy
Proportional Hazards Models
Multivariate Analysis
Therapeutics
Neoplasms

Keywords

  • Lung neoplasms/drug therapy
  • Lung neoplasms/surgery Lung neoplasms/radiotherapy
  • Survival analysis

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Debulking operation for non-small cell lung cancer. / Yilong, W.; Zhifan, H.; Tiehua, R.

In: Chinese Journal of Oncology, Vol. 19, No. 6, 01.12.1997, p. 442-444.

Research output: Contribution to journalArticle

Yilong, W, Zhifan, H & Tiehua, R 1997, 'Debulking operation for non-small cell lung cancer', Chinese Journal of Oncology, vol. 19, no. 6, pp. 442-444.
Yilong, W. ; Zhifan, H. ; Tiehua, R. / Debulking operation for non-small cell lung cancer. In: Chinese Journal of Oncology. 1997 ; Vol. 19, No. 6. pp. 442-444.
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