Depth-resolved measurements with elliptically polarized reflectance spectroscopy

Maria J. Bailey; Konstantin Sokolov

doi:10.1364/BOE.7.002861

Depth-resolved measurements with elliptically polarized reflectance spectroscopy

Maria J. Bailey, Konstantin Sokolov

Imaging Physics

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

The ability of elliptical polarized reflectance spectroscopy (EPRS) to detect spectroscopic alterations in tissue mimicking phantoms and in biological tissue in situ is demonstrated. It is shown that there is a linear relationship between light penetration depth and ellipticity. This dependence is used to demonstrate the feasibility of a depth-resolved spectroscopic imaging using EPRS. The advantages and drawbacks of EPRS in evaluation of biological tissue are analyzed and discussed.

Original language	English (US)
Article number	264191
Pages (from-to)	2861-2876
Number of pages	16
Journal	Biomedical Optics Express
Volume	7
Issue number	7
DOIs	https://doi.org/10.1364/BOE.7.002861
State	Published - Jul 1 2016

ASJC Scopus subject areas

Biotechnology
Atomic and Molecular Physics, and Optics

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10.1364/BOE.7.002861

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title = "Depth-resolved measurements with elliptically polarized reflectance spectroscopy",

abstract = "The ability of elliptical polarized reflectance spectroscopy (EPRS) to detect spectroscopic alterations in tissue mimicking phantoms and in biological tissue in situ is demonstrated. It is shown that there is a linear relationship between light penetration depth and ellipticity. This dependence is used to demonstrate the feasibility of a depth-resolved spectroscopic imaging using EPRS. The advantages and drawbacks of EPRS in evaluation of biological tissue are analyzed and discussed.",

author = "Bailey, {Maria J.} and Konstantin Sokolov",

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year = "2016",

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AU - Sokolov, Konstantin

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N2 - The ability of elliptical polarized reflectance spectroscopy (EPRS) to detect spectroscopic alterations in tissue mimicking phantoms and in biological tissue in situ is demonstrated. It is shown that there is a linear relationship between light penetration depth and ellipticity. This dependence is used to demonstrate the feasibility of a depth-resolved spectroscopic imaging using EPRS. The advantages and drawbacks of EPRS in evaluation of biological tissue are analyzed and discussed.

AB - The ability of elliptical polarized reflectance spectroscopy (EPRS) to detect spectroscopic alterations in tissue mimicking phantoms and in biological tissue in situ is demonstrated. It is shown that there is a linear relationship between light penetration depth and ellipticity. This dependence is used to demonstrate the feasibility of a depth-resolved spectroscopic imaging using EPRS. The advantages and drawbacks of EPRS in evaluation of biological tissue are analyzed and discussed.

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Depth-resolved measurements with elliptically polarized reflectance spectroscopy

Abstract

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