TY - CHAP
T1 - Diagnosis and molecular classification of lung cancer
AU - Rodriguez-Canales, Jaime
AU - Parra-Cuentas, Edwin
AU - Wistuba, Ignacio I.
PY - 2016/1/1
Y1 - 2016/1/1
N2 - Lung cancer is a complex disease composed of diverse histological and molecular types with clinical relevance. The advent of large-scale molecular profiling has been helpful to identify novel molecular targets that can be applied to the treatment of particular lung cancer patients and has helped to reshape the pathological classification of lung cancer. Novel directions include the immunotherapy revolution, which has opened the door for new opportunities for cancer therapy and is also redefining the classification of multiple tumors, including lung cancer. In the present chapter, we will review the main current basis of the pathological diagnosis and classification of lung cancer incorporating the histopathological and molecular dimensions of the disease.
AB - Lung cancer is a complex disease composed of diverse histological and molecular types with clinical relevance. The advent of large-scale molecular profiling has been helpful to identify novel molecular targets that can be applied to the treatment of particular lung cancer patients and has helped to reshape the pathological classification of lung cancer. Novel directions include the immunotherapy revolution, which has opened the door for new opportunities for cancer therapy and is also redefining the classification of multiple tumors, including lung cancer. In the present chapter, we will review the main current basis of the pathological diagnosis and classification of lung cancer incorporating the histopathological and molecular dimensions of the disease.
KW - Lung cancer
KW - Molecular targets
KW - Pathology classification
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U2 - 10.1007/978-3-319-40389-2_2
DO - 10.1007/978-3-319-40389-2_2
M3 - Chapter
C2 - 27535388
AN - SCOPUS:84983775899
T3 - Cancer Treatment and Research
SP - 25
EP - 46
BT - Cancer Treatment and Research
PB - Kluwer Academic Publishers
ER -