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Differential Sensitivities of Normal and Malignant Murine Lymphocytes to Purine Nucleosides

Research output: Contribution to journalArticlepeer-review

Abstract

Inherited human immunodeficiences associated with loss of adenosine deaminase or purine nucleoside phosphorylase are thought to result from accumulation of the nucleoside substrates. This work attempts to identify lymphocyte subpopulations that are uniquely-sensitive to the endogenous substrates or their analogs.

Original languageEnglish (US)
Pages (from-to)569-586
Number of pages18
JournalNucleosides and Nucleotides
Volume8
Issue number4
DOIs
StatePublished - Jan 1989

ASJC Scopus subject areas

  • Biochemistry
  • Genetics

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