Directed evolution of gold nanoparticle delivery to cells

Na Li; Timothy Larson; Hong H. Nguyen; Konstantin V. Sokolov; Andrew D. Ellington

doi:10.1039/b920865h

Directed evolution of gold nanoparticle delivery to cells

Na Li, Timothy Larson, Hong H. Nguyen, Konstantin V. Sokolov, Andrew D. Ellington

Research output: Contribution to journal › Article › peer-review

109 Scopus citations

Abstract

A newly selected anti-receptor (anti-EGFR) aptamer was conjugated to gold nanoparticles via a facile hybridization method and was found to specifically and quantitatively direct the delivery of gold nanoparticles to cells expressing EGFR through receptor-mediated endocytosis.

Original language	English (US)
Pages (from-to)	392-394
Number of pages	3
Journal	Chemical Communications
Volume	46
Issue number	3
DOIs	https://doi.org/10.1039/b920865h
State	Published - 2010
Externally published	Yes

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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10.1039/b920865h

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title = "Directed evolution of gold nanoparticle delivery to cells",

abstract = "A newly selected anti-receptor (anti-EGFR) aptamer was conjugated to gold nanoparticles via a facile hybridization method and was found to specifically and quantitatively direct the delivery of gold nanoparticles to cells expressing EGFR through receptor-mediated endocytosis.",

author = "Na Li and Timothy Larson and Nguyen, {Hong H.} and Sokolov, {Konstantin V.} and Ellington, {Andrew D.}",

year = "2010",

doi = "10.1039/b920865h",

language = "English (US)",

volume = "46",

pages = "392--394",

journal = "Chemical Communications",

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publisher = "Royal Society of Chemistry",

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T1 - Directed evolution of gold nanoparticle delivery to cells

AU - Li, Na

AU - Larson, Timothy

AU - Nguyen, Hong H.

AU - Sokolov, Konstantin V.

AU - Ellington, Andrew D.

PY - 2010

Y1 - 2010

N2 - A newly selected anti-receptor (anti-EGFR) aptamer was conjugated to gold nanoparticles via a facile hybridization method and was found to specifically and quantitatively direct the delivery of gold nanoparticles to cells expressing EGFR through receptor-mediated endocytosis.

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U2 - 10.1039/b920865h

DO - 10.1039/b920865h

M3 - Article

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VL - 46

SP - 392

EP - 394

JO - Chemical Communications

JF - Chemical Communications

IS - 3

ER -

Directed evolution of gold nanoparticle delivery to cells

Abstract

ASJC Scopus subject areas

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