Dosimetric comparison of 3DCRT, IMRT and VMAT for spine radiotherapy based on secondary cancer risk

Jalil ur Rehman; J. Ashraf; Muhammad Isa; Muhammad Afzal; G. Ibbott; James Chow

doi:10.1007/978-3-319-19387-8_154

Dosimetric comparison of 3DCRT, IMRT and VMAT for spine radiotherapy based on secondary cancer risk

Jalil ur Rehman, J. Ashraf, Muhammad Isa, Muhammad Afzal, G. Ibbott, James Chow

Radiation Physics

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

This study evaluated the secondary cancer risk after 3D-conformal radiotherapy (3DCRT), intensity modulated radiotherapy (IMRT) and volumetric modulated arc therapy (VMAT) for spine. Computed tomography image set of a RPC spine anthropomorphic phantom was exported to the Pinnacle3 treatment planning system. Radiation treatment plans for spine were created using the four-field 3DCRT, seven- field IMRT and dual-arc VMAT techniques. The mean and maximum doses, dose-volume histograms and volumes receiving more than 2 Gy and 4 Gy of organs-at-risk (OARs) were calculated and compared. The lifetime risk for secondary cancers was estimated according to NCRP Report 116. Quality Assurances of IMRT and VMAT were performed using the ArcCHECK method with gamma index criteria set to 3%/3mm. For our dosimetric comparisons, planning target volume coverages were found to be 90.5%, 91.4% and 95.9%, for 3DCRT, IMRT and VMAT, respectively. VMAT was found to deliver the lowest maximum dose to esophagus (3.22 Gy), bone (6.48 Gy), heart (1.69 Gy), spinal cord (5.15 Gy) and the whole lung (4.52 Gy). Volumes of esophagus receiving more than 4 Gy were 0% for VMAT, 37.56% for IMRT and up to 43.76% for 3DCRT. The estimated risk for secondary cancer in the respective OAR is considerably lower in VMAT compared to other techniques. Results of maximum doses and volumes of OARs suggest that the risk of secondary cancer induction for spine in VMAT is lower than IMRT and 3DCRT, whereas VMAT has the best target coverage.

Original language	English (US)
Title of host publication	World Congress on Medical Physics and Biomedical Engineering, 2015
Editors	David A. Jaffray
Publisher	Springer Verlag
Pages	633-636
Number of pages	4
ISBN (Print)	9783319193878
DOIs	https://doi.org/10.1007/978-3-319-19387-8_154
State	Published - 2015
Event	World Congress on Medical Physics and Biomedical Engineering, 2015 - Toronto, Canada Duration: Jun 7 2015 → Jun 12 2015

Publication series

Name	IFMBE Proceedings
Volume	51
ISSN (Print)	1680-0737

Other

Other	World Congress on Medical Physics and Biomedical Engineering, 2015
Country/Territory	Canada
City	Toronto
Period	6/7/15 → 6/12/15

Keywords

3DCRT
IMRT
Second cancer risk
Spine radiotherapy
VMAT

ASJC Scopus subject areas

Bioengineering
Biomedical Engineering

Access to Document

10.1007/978-3-319-19387-8_154

Cite this

ur Rehman, J., Ashraf, J., Isa, M., Afzal, M., Ibbott, G., & Chow, J. (2015). Dosimetric comparison of 3DCRT, IMRT and VMAT for spine radiotherapy based on secondary cancer risk. In D. A. Jaffray (Ed.), World Congress on Medical Physics and Biomedical Engineering, 2015 (pp. 633-636). (IFMBE Proceedings; Vol. 51). Springer Verlag. https://doi.org/10.1007/978-3-319-19387-8_154

Dosimetric comparison of 3DCRT, IMRT and VMAT for spine radiotherapy based on secondary cancer risk. / ur Rehman, Jalil; Ashraf, J.; Isa, Muhammad et al.
World Congress on Medical Physics and Biomedical Engineering, 2015. ed. / David A. Jaffray. Springer Verlag, 2015. p. 633-636 (IFMBE Proceedings; Vol. 51).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

ur Rehman, J, Ashraf, J, Isa, M, Afzal, M, Ibbott, G & Chow, J 2015, Dosimetric comparison of 3DCRT, IMRT and VMAT for spine radiotherapy based on secondary cancer risk. in DA Jaffray (ed.), World Congress on Medical Physics and Biomedical Engineering, 2015. IFMBE Proceedings, vol. 51, Springer Verlag, pp. 633-636, World Congress on Medical Physics and Biomedical Engineering, 2015, Toronto, Canada, 6/7/15. https://doi.org/10.1007/978-3-319-19387-8_154

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title = "Dosimetric comparison of 3DCRT, IMRT and VMAT for spine radiotherapy based on secondary cancer risk",

abstract = "This study evaluated the secondary cancer risk after 3D-conformal radiotherapy (3DCRT), intensity modulated radiotherapy (IMRT) and volumetric modulated arc therapy (VMAT) for spine. Computed tomography image set of a RPC spine anthropomorphic phantom was exported to the Pinnacle3 treatment planning system. Radiation treatment plans for spine were created using the four-field 3DCRT, seven- field IMRT and dual-arc VMAT techniques. The mean and maximum doses, dose-volume histograms and volumes receiving more than 2 Gy and 4 Gy of organs-at-risk (OARs) were calculated and compared. The lifetime risk for secondary cancers was estimated according to NCRP Report 116. Quality Assurances of IMRT and VMAT were performed using the ArcCHECK method with gamma index criteria set to 3%/3mm. For our dosimetric comparisons, planning target volume coverages were found to be 90.5%, 91.4% and 95.9%, for 3DCRT, IMRT and VMAT, respectively. VMAT was found to deliver the lowest maximum dose to esophagus (3.22 Gy), bone (6.48 Gy), heart (1.69 Gy), spinal cord (5.15 Gy) and the whole lung (4.52 Gy). Volumes of esophagus receiving more than 4 Gy were 0% for VMAT, 37.56% for IMRT and up to 43.76% for 3DCRT. The estimated risk for secondary cancer in the respective OAR is considerably lower in VMAT compared to other techniques. Results of maximum doses and volumes of OARs suggest that the risk of secondary cancer induction for spine in VMAT is lower than IMRT and 3DCRT, whereas VMAT has the best target coverage.",

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author = "{ur Rehman}, Jalil and J. Ashraf and Muhammad Isa and Muhammad Afzal and G. Ibbott and James Chow",

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AU - ur Rehman, Jalil

AU - Ashraf, J.

AU - Isa, Muhammad

AU - Afzal, Muhammad

AU - Ibbott, G.

AU - Chow, James

N1 - Publisher Copyright: © Springer International Publishing Switzerland 2015.

PY - 2015

Y1 - 2015

N2 - This study evaluated the secondary cancer risk after 3D-conformal radiotherapy (3DCRT), intensity modulated radiotherapy (IMRT) and volumetric modulated arc therapy (VMAT) for spine. Computed tomography image set of a RPC spine anthropomorphic phantom was exported to the Pinnacle3 treatment planning system. Radiation treatment plans for spine were created using the four-field 3DCRT, seven- field IMRT and dual-arc VMAT techniques. The mean and maximum doses, dose-volume histograms and volumes receiving more than 2 Gy and 4 Gy of organs-at-risk (OARs) were calculated and compared. The lifetime risk for secondary cancers was estimated according to NCRP Report 116. Quality Assurances of IMRT and VMAT were performed using the ArcCHECK method with gamma index criteria set to 3%/3mm. For our dosimetric comparisons, planning target volume coverages were found to be 90.5%, 91.4% and 95.9%, for 3DCRT, IMRT and VMAT, respectively. VMAT was found to deliver the lowest maximum dose to esophagus (3.22 Gy), bone (6.48 Gy), heart (1.69 Gy), spinal cord (5.15 Gy) and the whole lung (4.52 Gy). Volumes of esophagus receiving more than 4 Gy were 0% for VMAT, 37.56% for IMRT and up to 43.76% for 3DCRT. The estimated risk for secondary cancer in the respective OAR is considerably lower in VMAT compared to other techniques. Results of maximum doses and volumes of OARs suggest that the risk of secondary cancer induction for spine in VMAT is lower than IMRT and 3DCRT, whereas VMAT has the best target coverage.

AB - This study evaluated the secondary cancer risk after 3D-conformal radiotherapy (3DCRT), intensity modulated radiotherapy (IMRT) and volumetric modulated arc therapy (VMAT) for spine. Computed tomography image set of a RPC spine anthropomorphic phantom was exported to the Pinnacle3 treatment planning system. Radiation treatment plans for spine were created using the four-field 3DCRT, seven- field IMRT and dual-arc VMAT techniques. The mean and maximum doses, dose-volume histograms and volumes receiving more than 2 Gy and 4 Gy of organs-at-risk (OARs) were calculated and compared. The lifetime risk for secondary cancers was estimated according to NCRP Report 116. Quality Assurances of IMRT and VMAT were performed using the ArcCHECK method with gamma index criteria set to 3%/3mm. For our dosimetric comparisons, planning target volume coverages were found to be 90.5%, 91.4% and 95.9%, for 3DCRT, IMRT and VMAT, respectively. VMAT was found to deliver the lowest maximum dose to esophagus (3.22 Gy), bone (6.48 Gy), heart (1.69 Gy), spinal cord (5.15 Gy) and the whole lung (4.52 Gy). Volumes of esophagus receiving more than 4 Gy were 0% for VMAT, 37.56% for IMRT and up to 43.76% for 3DCRT. The estimated risk for secondary cancer in the respective OAR is considerably lower in VMAT compared to other techniques. Results of maximum doses and volumes of OARs suggest that the risk of secondary cancer induction for spine in VMAT is lower than IMRT and 3DCRT, whereas VMAT has the best target coverage.

KW - 3DCRT

KW - IMRT

KW - Second cancer risk

KW - Spine radiotherapy

KW - VMAT

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T3 - IFMBE Proceedings

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BT - World Congress on Medical Physics and Biomedical Engineering, 2015

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PB - Springer Verlag

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Y2 - 7 June 2015 through 12 June 2015

ER -

Dosimetric comparison of 3DCRT, IMRT and VMAT for spine radiotherapy based on secondary cancer risk

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