Dosimetric feasibility of an anthropomorphic three-dimensional PRESAGE® dosimeter for verification of single entry hybrid catheter accelerated partial breast brachytherapy

Khalid Iqbal, Geoffrey S. Ibbott, Ryan G. Lafratta, Kent A. Gifford, Muhammad Akram, Saeed A. Buzdar

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Purpose To determine the feasibility of an anthropomorphic breast polyurethane-based three-dimensional (3D) dosimeter with cavity to measure dose distributions and skin dose for a commercial strut-based applicator strut-adjusted volume implant (SAVI™) 6-1.Materials and methods An anthropomorphic breast 3D dosimeter was created with a cavity to accommodate the SAVI™ strut-based device. 2 Gy was prescribed to the breast dosimeter having D 95 to planning target volume evaluation (PTV_EVAL) while limiting 125% of the prescribed dose to the skin. Independent dose distribution verification was performed with GAFCHROMIC® EBT2 film. The dose distribution from the 3D dosimeter was compared to the distributions from commercial brachytherapy treatment planning system (TPS) and film. Point skin doses, line profiles and dose-volume histogram (DVHs) for the skin and PTV_EVAL were compared.Results The maximum difference in skin dose for TPS and the 3D dosimeter was 4% whereas 41% between the TPS and EBT2 film. The maximum dose difference for line profiles between TPS, 3D dosimeter, and film was 4·1%. DVHs of skin and PTV_EVAL for TPS and 3D dosimeter differed by a maximum of 4% at 5 mm depth and skin differed by a maximum 1·5% between TPS and 3D dosimeter. The criterion for gamma analysis comparison was 92·5% at ±5%±3 mm criterion. The TPS demonstrated at least ±5% comparability in predicting dose to the skin, PTV_EVAL and normal breast tissue.Conclusions 3D anthropomorphic polyurethane dosimeter with cavity gives comparable results to the TPS dose predictions and GAFCHROMIC® EBT2 film results in the context of HDR brachytherapy.

Original languageEnglish (US)
Pages (from-to)403-410
Number of pages8
JournalJournal of Radiotherapy in Practice
Volume17
Issue number4
DOIs
StatePublished - Dec 1 2018

Keywords

  • EBT2 GAFCHROMIC film
  • brachytherapy
  • breast PRESAGE
  • dosimetry
  • partial breast irradiation

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Oncology

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