Ductal Carcinoma In Situ: Treatment Update and Current Trends

Katrina B. Mitchell, Henry Kuerer

Research output: Contribution to journalReview articlepeer-review

23 Scopus citations

Abstract

Ductal carcinoma in situ (DCIS) traditionally has been managed through various combinations of surgery, radiation, and endocrine therapy. However, concern for under- or over-treatment of DCIS has led many surgeons to question historically standardized approaches and instead begin to tailor treatment based on individual prognostic indicators. Recent and ongoing clinical trials have investigated the potential for active surveillance in DCIS, the possibility of eliminating radiation therapy (RT), and ways in which adjuvant systemic therapy may be refined. This review will summarize the current trends in the treatment of DCIS, as well as highlight the most pertinent clinical trials that are shaping management today.

Original languageEnglish (US)
Article number48
JournalCurrent oncology reports
Volume17
Issue number11
DOIs
StatePublished - Nov 22 2015

Keywords

  • Accelerated partial breast irradiation
  • Anastrozole
  • Breast cancer therapy
  • Breast pathology
  • Breast radiation
  • Breast surgery
  • Breast-conserving therapy
  • Clinical trials
  • Contralateral mastectomy
  • DCIS
  • Ductal carcinoma in situ
  • Mastectomy
  • Tamoxifen

ASJC Scopus subject areas

  • Oncology

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