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Keyphrases
Phase I Trial
100%
Monotherapy
100%
Fibroblast Growth Factor Receptor 1 (FGFR1)
100%
Metastatic Cholangiocarcinoma
100%
Tinengotinib
100%
FGFR Inhibitor
71%
FGFR2 Fusion
71%
Cholangiocarcinoma
57%
FGFR Alteration
57%
Treatment-related
42%
In(III)
42%
Tumor Reduction
42%
Eastern Cooperative Oncology Group Performance Status (ECOG PS)
28%
Prior Chemotherapy
28%
Inhibitor Therapy
28%
Non-fusion
28%
Phase I Study
14%
Diarrhea
14%
Clinical Benefit
14%
Safety Assessment
14%
Common Terminology Criteria for Adverse Events (CTCAE)
14%
Clinical Efficacy
14%
Acquired Resistance
14%
Objective Response Rate
14%
Systemic Chemotherapy
14%
Hypertension
14%
Binding Properties
14%
Stomatitis
14%
Clinical Model
14%
Fibroblast Growth Factor Receptor 2 (FGFR2)
14%
Clinical Trial Data
14%
Safety Impact
14%
Modified Response Evaluation Criteria in Solid Tumors (mRECIST)
14%
Multikinase Inhibitor
14%
Pharmacodynamic Interactions
14%
B-13
14%
Lipase
14%
Resistant mutation
14%
Palmar-plantar Erythrodysesthesia
14%
Posterior Reversible Encephalopathy Syndrome
14%
Spectrally Selective
14%
Patient Treatment
14%
Median Progression-free Survival
14%
Control Phase
14%
Relapsed/refractory
14%
Efficacy Safety
14%
Physician Choice
14%
Medicine and Dentistry
Clinical Trial
100%
Monotherapy
100%
Cholangiocarcinoma
100%
Fibroblast Growth Factor Receptor 2
100%
Fibroblast Growth Factor Receptor 1
100%
Neoplasm
50%
Patient History of Chemotherapy
33%
Electrocorticography
33%
Phase I Trials
16%
Progression Free Survival
16%
Diarrhea
16%
Chemotherapy
16%
Hand Foot Syndrome
16%
Pharmacodynamics
16%
Phosphotransferase Inhibitor
16%
Triacylglycerol Lipase
16%
Posterior Reversible Encephalopathy Syndrome
16%
Safety Assessment
16%
Hypertension
16%
Stomatitis
16%
Pharmacology, Toxicology and Pharmaceutical Science
Clinical Trial
100%
Monotherapy
100%
Bile Duct Carcinoma
100%
Fibroblast Growth Factor Receptor 1
100%
Fibroblast Growth Factor Receptor 2
100%
Neoplasm
50%
Patient History of Chemotherapy
33%
Phase I Trials
16%
Diarrhea
16%
Safety Assessment
16%
Syndrome
16%
Progression Free Survival
16%
Phosphotransferase Inhibitor
16%
Hand Foot Syndrome
16%
Pharmacodynamics
16%
Pancreatic Lipase
16%
Posterior Reversible Encephalopathy Syndrome
16%
Chemotherapy Regimen
16%
Hypertension
16%
Stomatitis
16%
Biochemistry, Genetics and Molecular Biology
Clinical Trial
100%
Fibroblast Growth Factor Receptor 2
100%
Fibroblast Growth Factor Receptor 1
100%
Wild Type
33%
Electrocorticography
33%
Kinase
16%
Phosphotransferase
16%
Phase I Trials
16%
Progression Free Survival
16%
Pharmacodynamics
16%
Triacylglycerol Lipase
16%
Pancreatic Lipase
16%
Stomatitis
16%