TY - JOUR
T1 - Electrolyte Disturbances in Critically Ill Cancer Patients
T2 - An Endocrine Perspective
AU - Khan, Maryam I.
AU - Dellinger, R. Phillip
AU - Waguespack, Steven G.
N1 - Publisher Copyright:
© 2017, © The Author(s) 2017.
PY - 2018/3/1
Y1 - 2018/3/1
N2 - Electrolyte disturbances are frequently encountered in critically ill oncology patients. Hyponatremia and hypernatremia as well as hypocalcemia and hypercalcemia are among the most commonly encountered electrolyte abnormalities. In the intensive care unit, management of critical electrolyte disturbances is focused on initial evaluation and immediate treatment plan to prevent severe complications. A PubMed search was performed to identify best available evidence for evaluation and management of dysnatremias, hypocalcemia, and hypercalcemia. Current literature was reviewed regarding the management of electrolyte disturbances. The role of new therapeutic options, for example, vaptans for hyponatremia, teriparatide for hypocalcemia, and denosumab for hypercalcemia, is discussed. Early diagnosis and appropriate management are expected to reduce adverse outcomes.
AB - Electrolyte disturbances are frequently encountered in critically ill oncology patients. Hyponatremia and hypernatremia as well as hypocalcemia and hypercalcemia are among the most commonly encountered electrolyte abnormalities. In the intensive care unit, management of critical electrolyte disturbances is focused on initial evaluation and immediate treatment plan to prevent severe complications. A PubMed search was performed to identify best available evidence for evaluation and management of dysnatremias, hypocalcemia, and hypercalcemia. Current literature was reviewed regarding the management of electrolyte disturbances. The role of new therapeutic options, for example, vaptans for hyponatremia, teriparatide for hypocalcemia, and denosumab for hypercalcemia, is discussed. Early diagnosis and appropriate management are expected to reduce adverse outcomes.
KW - hypercalcemia
KW - hypernatremia
KW - hypocalcemia
KW - hyponatremia
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U2 - 10.1177/0885066617706650
DO - 10.1177/0885066617706650
M3 - Review article
C2 - 28535742
AN - SCOPUS:85041612821
SN - 0885-0666
VL - 33
SP - 147
EP - 158
JO - Journal of Intensive Care Medicine
JF - Journal of Intensive Care Medicine
IS - 3
ER -