Electron conformal radiotherapy using bolus and intensity modulation

Rajat J Kudchadker, Kenneth R. Hogstrom, Adam S Garden, Marsha D. McNeese, Robert A. Boyd, John A. Antolak

Research output: Contribution to journalArticle

43 Citations (Scopus)

Abstract

Purpose: Conformal electron beam therapy can be delivered using shaped bolus, which varies the penetration of the electrons across the incident beam so that the 90% isodose surface conforms to the distal surface of the planning target volume (PTV). Previous use of this modality has shown that the irregular proximal surface of the bolus causes the dose heterogeneity in the PTV to increase from 10%, the typical dose spread of a flat-water surface to approximately 20%. The present work evaluates the ability to restore dose homogeneity by varying the incident electron intensity. Methods and Materials: Three patients, one each with chest wall, thorax, and head-and-neck cancer, were planned using electron conformal therapy with bolus, with and without intensity modulation. Resulting dose distributions and dose-volume histograms were compared with non-intensity-modulated bolus plans. Results: In all cases, the ΔD90%-10% for the PTV was reduced; for example, for the head-and-neck case, the ΔD90%-10% for the PTV was reduced from 14.9% to 9.2%. This reduction in dose spread is a direct result of intensity modulation. Conclusions: The results showed that intensity-modulated electron beams could significantly improve the dose homogeneity in the PTV for patients treated with electron conformal therapy using shaped bolus.

Original languageEnglish (US)
Pages (from-to)1023-1037
Number of pages15
JournalInternational Journal of Radiation Oncology Biology Physics
Volume53
Issue number4
DOIs
StatePublished - Jul 15 2002

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Conformal Radiotherapy
radiation therapy
Electrons
modulation
dosage
planning
electrons
therapy
homogeneity
electron beams
electron flux density
thorax
Thoracic Wall
Head and Neck Neoplasms
chest
surface water
histograms
Neck
Thorax
Therapeutics

Keywords

  • Electron bolus
  • Electron conformal therapy
  • Intensity modulation

ASJC Scopus subject areas

  • Radiation
  • Oncology
  • Radiology Nuclear Medicine and imaging
  • Cancer Research

Cite this

Electron conformal radiotherapy using bolus and intensity modulation. / Kudchadker, Rajat J; Hogstrom, Kenneth R.; Garden, Adam S; McNeese, Marsha D.; Boyd, Robert A.; Antolak, John A.

In: International Journal of Radiation Oncology Biology Physics, Vol. 53, No. 4, 15.07.2002, p. 1023-1037.

Research output: Contribution to journalArticle

Kudchadker, Rajat J ; Hogstrom, Kenneth R. ; Garden, Adam S ; McNeese, Marsha D. ; Boyd, Robert A. ; Antolak, John A. / Electron conformal radiotherapy using bolus and intensity modulation. In: International Journal of Radiation Oncology Biology Physics. 2002 ; Vol. 53, No. 4. pp. 1023-1037.
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