Embryonal rhabdomyosarcoma of the paranasal sinuses: A case report and review of literature

Pei Xue Wu, Yan Fang Liang, Jian Bo Ruan, Dong Ping Kang, Can Chen, Jin Cheng Zeng, Tao Zeng, Qiu Liang Wu, Wei Hua Xu

    Research output: Contribution to journalArticle

    3 Scopus citations

    Abstract

    Embryonal rhabdomyosarcoma (ERMS) is a rare malignancy with a poor outcome. In this article, we describe a case of ERMS in the paranasal sinuses from a 60-year-old male patient. ERMS derived from the paranasal sinuses is extremely rare. The diagnosis of ERMS must be based on histological findings and immunohistochemical findings. In this case, microscopic observation showed tumor cells were arranged in flocked sheets, cord-like and acinar-like by hyperplastic fibrous tissue. And ERMS tissues were immunopositive for myogenin, desmin, MSA, CD56, vimentin, CD99, Syn and Ki-67 (40%+), and immunonegative for CK, EMA, LCA, GFAP, NSE, S-100, HMB-45 and Melan-A. Here, the patient was treated with multimodal therapy including endoscopic surgery, chemotherapy and radiation, but the patient’s postoperative recovery is not too smooth.

    Original languageEnglish (US)
    Pages (from-to)2369-2372
    Number of pages4
    JournalInternational Journal of Clinical and Experimental Medicine
    Volume7
    Issue number8
    StatePublished - Aug 30 2014

    Keywords

    • Embryonal rhabdomyosarcoma
    • Immunohistochemistry
    • Paranasal sinuses

    ASJC Scopus subject areas

    • Biochemistry, Genetics and Molecular Biology(all)

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  • Cite this

    Wu, P. X., Liang, Y. F., Ruan, J. B., Kang, D. P., Chen, C., Zeng, J. C., Zeng, T., Wu, Q. L., & Xu, W. H. (2014). Embryonal rhabdomyosarcoma of the paranasal sinuses: A case report and review of literature. International Journal of Clinical and Experimental Medicine, 7(8), 2369-2372.