TY - JOUR
T1 - Emerging Magnetic Resonance Imaging Technologies for Radiation Therapy Planning and Response Assessment
AU - Jones, Kyle M.
AU - Michel, Keith A.
AU - Bankson, James A.
AU - Fuller, Clifton D.
AU - Klopp, Ann H.
AU - Venkatesan, Aradhana M.
N1 - Funding Information:
Research described in this review and performed by the authors was supported by grant support from Toshiba America Medical Systems, the RSNA Research and Education Foundation, the National Cancer Institute (P30-CA016672), and by institutional funds from the University of Texas MD Anderson Cancer Center.
Publisher Copyright:
© 2018
PY - 2018/8/1
Y1 - 2018/8/1
N2 - Functional and molecular MRI techniques are capable of measuring biologic properties of tumor tissue. Knowledge of these biological properties may improve radiation treatment by more accurately identifying tumor volumes, characterizing radioresistant subvolumes of tumor before radiation therapy (RT), and identifying recurrent disease after RT. Intravoxel incoherent motion MRI, blood oxygenation level–dependent MRI, tissue oxygenation level–dependent MRI, hyperpolarized 13 C MRI, and chemical exchange saturation transfer MRI are relatively new MRI techniques that have shown promise for contributing to RT planning and response assessment. This review critically evaluates these emerging MR techniques, their potential role in RT planning, utility to date, and challenges to integration into the current clinical workflow.
AB - Functional and molecular MRI techniques are capable of measuring biologic properties of tumor tissue. Knowledge of these biological properties may improve radiation treatment by more accurately identifying tumor volumes, characterizing radioresistant subvolumes of tumor before radiation therapy (RT), and identifying recurrent disease after RT. Intravoxel incoherent motion MRI, blood oxygenation level–dependent MRI, tissue oxygenation level–dependent MRI, hyperpolarized 13 C MRI, and chemical exchange saturation transfer MRI are relatively new MRI techniques that have shown promise for contributing to RT planning and response assessment. This review critically evaluates these emerging MR techniques, their potential role in RT planning, utility to date, and challenges to integration into the current clinical workflow.
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U2 - 10.1016/j.ijrobp.2018.03.028
DO - 10.1016/j.ijrobp.2018.03.028
M3 - Review article
C2 - 30012524
AN - SCOPUS:85049438026
SN - 0360-3016
VL - 101
SP - 1046
EP - 1056
JO - International Journal of Radiation Oncology Biology Physics
JF - International Journal of Radiation Oncology Biology Physics
IS - 5
ER -