EMT: Matter of Life or Death?

Sonal Gupta; Anirban Maitra

doi:10.1016/j.cell.2016.02.024

EMT: Matter of Life or Death?

Sonal Gupta, Anirban Maitra

Pathology

Research output: Contribution to journal › Short survey › peer-review

45 Scopus citations

Abstract

TGF-β is long considered a "protean" cytokine in cancer, changing its role from anti- to pro-tumorigenic in a context-dependent manner. In this issue of Cell, David et al. use mouse models of pancreatic cancer to shed light on the mechanistic basis of how TGF-β-induced EMT is coupled to either apoptosis or tumor progression.

Original language	English (US)
Pages (from-to)	840-842
Number of pages	3
Journal	Cell
Volume	164
Issue number	5
DOIs	https://doi.org/10.1016/j.cell.2016.02.024
State	Published - Feb 25 2016

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

Access to Document

10.1016/j.cell.2016.02.024

Cite this

@article{9cbc203efc2249cf89ecae5a08bbfb9b,

title = "EMT: Matter of Life or Death?",

abstract = "TGF-β is long considered a {"}protean{"} cytokine in cancer, changing its role from anti- to pro-tumorigenic in a context-dependent manner. In this issue of Cell, David et al. use mouse models of pancreatic cancer to shed light on the mechanistic basis of how TGF-β-induced EMT is coupled to either apoptosis or tumor progression.",

author = "Sonal Gupta and Anirban Maitra",

note = "Publisher Copyright: {\textcopyright} 2016 Elsevier Inc.",

year = "2016",

month = feb,

day = "25",

doi = "10.1016/j.cell.2016.02.024",

language = "English (US)",

volume = "164",

pages = "840--842",

journal = "Cell",

issn = "0092-8674",

publisher = "Cell Press",

number = "5",

}

TY - JOUR

T1 - EMT

T2 - Matter of Life or Death?

AU - Gupta, Sonal

AU - Maitra, Anirban

PY - 2016/2/25

Y1 - 2016/2/25

N2 - TGF-β is long considered a "protean" cytokine in cancer, changing its role from anti- to pro-tumorigenic in a context-dependent manner. In this issue of Cell, David et al. use mouse models of pancreatic cancer to shed light on the mechanistic basis of how TGF-β-induced EMT is coupled to either apoptosis or tumor progression.

AB - TGF-β is long considered a "protean" cytokine in cancer, changing its role from anti- to pro-tumorigenic in a context-dependent manner. In this issue of Cell, David et al. use mouse models of pancreatic cancer to shed light on the mechanistic basis of how TGF-β-induced EMT is coupled to either apoptosis or tumor progression.

UR - http://www.scopus.com/inward/record.url?scp=84959422909&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84959422909&partnerID=8YFLogxK

U2 - 10.1016/j.cell.2016.02.024

DO - 10.1016/j.cell.2016.02.024

M3 - Short survey

C2 - 26919422

AN - SCOPUS:84959422909

SN - 0092-8674

VL - 164

SP - 840

EP - 842

JO - Cell

JF - Cell

IS - 5

ER -

EMT: Matter of Life or Death?

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this