Endometrial Carcinoma, Grossing and Processing Issues: Recommendations of the International Society of Gynecologic Pathologists

Anais Malpica, Elizabeth D. Euscher, Jonathan L. Hecht, Rouba Ali-Fehmi, Charles M. Quick, Naveena Singh, Lars Christian Horn, Isabel Alvarado-Cabrero, Xavier Matias-Guiu, Lynn Hirschowitz, Máire Duggan, Jaume Ordi, Vinita Parkash, Yoshiki Mikami, M. Ruhul Quddus, Richard Zaino, Annette Staebler, Charles Zaloudek, W. Glenn McCluggage, Esther Oliva

Research output: Contribution to journalArticlepeer-review

50 Scopus citations

Abstract

Endometrial cancer is the most common gynecologic neoplasm in developed countries; however, updated universal guidelines are currently not available to handle specimens obtained during the surgical treatment of patients affected by this disease. This article presents recommendations on how to gross and submit sections for microscopic examination of hysterectomy specimens and other tissues removed during the surgical management of endometrial cancer such as salpingo-oophorectomy, omentectomy, and lymph node dissection-including sentinel lymph nodes. In addition, the intraoperative assessment of some of these specimens is addressed. These recommendations are based on a review of the literature, grossing manuals from various institutions, and a collaborative effort by a subgroup of the Endometrial Cancer Task Force of the International Society of Gynecological Pathologists. The aim of these recommendations is to standardize the processing of endometrial cancer specimens which is vital for adequate pathological reporting and will ultimately improve our understanding of this disease.

Original languageEnglish (US)
Pages (from-to)S9-S24
JournalInternational Journal of Gynecological Pathology
Volume38
Issue number1
DOIs
StatePublished - Jan 1 2019

Keywords

  • Endometrial carcinoma
  • Gross examination
  • Lymph nodes
  • Macroscopic examination
  • Pathology
  • Processing
  • Sentinel lymph nodes
  • Staging
  • Tumor size

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Obstetrics and Gynecology

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