Endoscopic Management of GI Endoscopic Mucosal Resection and Endoscopic Submucosal Dissection Perforations

Endoscopic closure of gastrointestinal (GI) tract perforations, whether by clips or sutures, has revolutionized endoluminal surgery. It allows us to close perforations immediately, thereby eliminating the need for surgery and the morbidity and mortality associated with it. Soehendra’s group’s first successful closure of a gastric perforation after endoscopic resection of a leiomyoma in the 1990s opened up the field of endoscopic surgery. 1 In this chapter, we review endoscopic devices and closure techniques, and both animal and clinical studies on endoscopic closure of perforations.