Endotoxin inhibits the fluoride-stimulated adenylate cyclase activity of rat liver plasma membranes enriched with bile canaliculi

R. Utili; A. Di Donato; G. Draetta; G. Paolisso; C. O. Abernathy; G. Illiano

doi:10.1007/BF01972299

Endotoxin inhibits the fluoride-stimulated adenylate cyclase activity of rat liver plasma membranes enriched with bile canaliculi

R. Utili
, A. Di Donato
, G. Draetta
, G. Paolisso
, C. O. Abernathy
, G. Illiano

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Escherichia coli endotoxin inhibited the fluoride-stimulated adenylate cyclase activity of liver plasma membranes enriched with bile canaliculi. Inhibition was of a mixed competitive and uncompetitive type. This effect, which may result from changes of membrane organization, may have relevance in the understanding of endotoxin-cell membrane interactions.

Original language	English (US)
Pages (from-to)	831-833
Number of pages	3
Journal	Experientia
Volume	38
Issue number	7
DOIs	https://doi.org/10.1007/BF01972299
State	Published - Jul 1982
Externally published	Yes

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

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10.1007/BF01972299

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title = "Endotoxin inhibits the fluoride-stimulated adenylate cyclase activity of rat liver plasma membranes enriched with bile canaliculi",

abstract = "Escherichia coli endotoxin inhibited the fluoride-stimulated adenylate cyclase activity of liver plasma membranes enriched with bile canaliculi. Inhibition was of a mixed competitive and uncompetitive type. This effect, which may result from changes of membrane organization, may have relevance in the understanding of endotoxin-cell membrane interactions.",

author = "R. Utili and \{Di Donato\}, A. and G. Draetta and G. Paolisso and Abernathy, \{C. O.\} and G. Illiano",

year = "1982",

month = jul,

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language = "English (US)",

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AU - Utili, R.

AU - Di Donato, A.

AU - Draetta, G.

AU - Paolisso, G.

AU - Abernathy, C. O.

AU - Illiano, G.

PY - 1982/7

Y1 - 1982/7

N2 - Escherichia coli endotoxin inhibited the fluoride-stimulated adenylate cyclase activity of liver plasma membranes enriched with bile canaliculi. Inhibition was of a mixed competitive and uncompetitive type. This effect, which may result from changes of membrane organization, may have relevance in the understanding of endotoxin-cell membrane interactions.

AB - Escherichia coli endotoxin inhibited the fluoride-stimulated adenylate cyclase activity of liver plasma membranes enriched with bile canaliculi. Inhibition was of a mixed competitive and uncompetitive type. This effect, which may result from changes of membrane organization, may have relevance in the understanding of endotoxin-cell membrane interactions.

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U2 - 10.1007/BF01972299

DO - 10.1007/BF01972299

M3 - Article

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AN - SCOPUS:0019935170

SN - 0014-4754

VL - 38

SP - 831

EP - 833

JO - Experientia

JF - Experientia

IS - 7

ER -

Endotoxin inhibits the fluoride-stimulated adenylate cyclase activity of rat liver plasma membranes enriched with bile canaliculi

Abstract

ASJC Scopus subject areas

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