Enhancement of radiation effects by bismuth oxide nanoparticles for kilovoltage x-ray beams: A dosimetric study using a novel multi-compartment 3D radiochromic dosimeter

M. Alqathami; A. Blencowe; U. J. Yeo; R. Franich; S. Doran; G. Qiao; M. Geso

doi:10.1088/1742-6596/444/1/012025

Enhancement of radiation effects by bismuth oxide nanoparticles for kilovoltage x-ray beams: A dosimetric study using a novel multi-compartment 3D radiochromic dosimeter

M. Alqathami, A. Blencowe, U. J. Yeo, R. Franich, S. Doran, G. Qiao, M. Geso

Radiation Physics

Research output: Contribution to journal › Conference article › peer-review

36 Scopus citations

Abstract

The aim of this study is to present the first experimental validation and quantification of the dose enhancement capability of bismuth oxide nanoparticles (Bi₂O₃-Nps). A recently introduced multi-compartment 3D radiochromic dosimeter for measuring radiation dose enhancement produced from the interaction of X-rays with metal nanoparticles was employed to investigate the 3D spatial distribution of ionizing radiation dose deposition. Dose-enhancement factor for the dosimeters doped with Bi₂O ₃-NPs was ∼1.9 for both spectrophotometry and optical CT analyses. Our results suggest that bismuth-based nanomaterials are efficient dose enhancing agents and have great potential for application in clinical radiotherapy.

Original language	English (US)
Article number	012025
Journal	Journal of Physics: Conference Series
Volume	444
Issue number	1
DOIs	https://doi.org/10.1088/1742-6596/444/1/012025
State	Published - 2013
Event	7th International Conference on 3D Radiation Dosimetry, IC3DDose 2012 - Sydney, NSW, Australia Duration: Dec 4 2012 → Dec 8 2012

ASJC Scopus subject areas

General Physics and Astronomy

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10.1088/1742-6596/444/1/012025

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Alqathami, M., Blencowe, A., Yeo, U. J., Franich, R., Doran, S., Qiao, G., & Geso, M. (2013). Enhancement of radiation effects by bismuth oxide nanoparticles for kilovoltage x-ray beams: A dosimetric study using a novel multi-compartment 3D radiochromic dosimeter. Journal of Physics: Conference Series, 444(1), Article 012025. https://doi.org/10.1088/1742-6596/444/1/012025

Enhancement of radiation effects by bismuth oxide nanoparticles for kilovoltage x-ray beams: A dosimetric study using a novel multi-compartment 3D radiochromic dosimeter. / Alqathami, M.; Blencowe, A.; Yeo, U. J. et al.
In: Journal of Physics: Conference Series, Vol. 444, No. 1, 012025, 2013.

Research output: Contribution to journal › Conference article › peer-review

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abstract = "The aim of this study is to present the first experimental validation and quantification of the dose enhancement capability of bismuth oxide nanoparticles (Bi2O3-Nps). A recently introduced multi-compartment 3D radiochromic dosimeter for measuring radiation dose enhancement produced from the interaction of X-rays with metal nanoparticles was employed to investigate the 3D spatial distribution of ionizing radiation dose deposition. Dose-enhancement factor for the dosimeters doped with Bi2O 3-NPs was ∼1.9 for both spectrophotometry and optical CT analyses. Our results suggest that bismuth-based nanomaterials are efficient dose enhancing agents and have great potential for application in clinical radiotherapy.",

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T2 - 7th International Conference on 3D Radiation Dosimetry, IC3DDose 2012

AU - Alqathami, M.

AU - Blencowe, A.

AU - Yeo, U. J.

AU - Franich, R.

AU - Doran, S.

AU - Qiao, G.

AU - Geso, M.

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AB - The aim of this study is to present the first experimental validation and quantification of the dose enhancement capability of bismuth oxide nanoparticles (Bi2O3-Nps). A recently introduced multi-compartment 3D radiochromic dosimeter for measuring radiation dose enhancement produced from the interaction of X-rays with metal nanoparticles was employed to investigate the 3D spatial distribution of ionizing radiation dose deposition. Dose-enhancement factor for the dosimeters doped with Bi2O 3-NPs was ∼1.9 for both spectrophotometry and optical CT analyses. Our results suggest that bismuth-based nanomaterials are efficient dose enhancing agents and have great potential for application in clinical radiotherapy.

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Enhancement of radiation effects by bismuth oxide nanoparticles for kilovoltage x-ray beams: A dosimetric study using a novel multi-compartment 3D radiochromic dosimeter

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