Evaluation of heterogeneity corrections in stereotactic body radiation therapy for the lung

Yukinori Matsuo, Yuichiro Narita, Manabu Nakata, Mitsuhiro Nakamura, Yasushi Nagata, Takashi Mizowaki, Kenji Takayama, Yoshiki Norihisa, Masaru Narabayashi, Masahiro Hiraoka

    Research output: Contribution to journalArticle


    Purpose: The purpose was to evaluate impact of heterogeneity corrections on dose distributions for stereotactic body radiation therapy (SBRT) for the lung. Materials and Methods: This study was conducted with the treatment plans of 28 cases in which we performed SBRT for solitary lung tumors with 48 Gy in 12-Gy fractions at the isocenter. The treatment plans were recalculated under three conditions of heterogeneity correction as follows: pencil beam convolution with Batho power law correction (PBC-BPL), pencil beam convolution with no correction (PBC-NC), and anisotropic analytical algorithm with heterogeneity correction (AAA). Dose-volumetric data were compared among the three conditions. Results: Heterogeneity corrections had a significant impact on all dose-volumetric parameters. Means of isocenter dose were 48.0 Gy, 44.6 Gy, and 48.4 Gy in PBC-BPL, PBC-NC, and AAA, respectively. PTV D95 were 45.2 Gy, 41.1 Gy, and 42.1 Gy, and V20 of the lung were 4.1%, 3.7%, and 3.9%, respectively. Conclusion: Significant differences in dose distribution were observed among heterogeneity corrections. Attention needs to be paid to the differences.

    Original languageEnglish (US)
    Pages (from-to)151-154
    Number of pages4
    JournalJournal of JASTRO
    Issue number4
    StatePublished - Dec 1 2008



    • Heterogeneity correction
    • Lung
    • Stereotactic body radiation therapy

    ASJC Scopus subject areas

    • Radiology Nuclear Medicine and imaging
    • Oncology

    Cite this

    Matsuo, Y., Narita, Y., Nakata, M., Nakamura, M., Nagata, Y., Mizowaki, T., Takayama, K., Norihisa, Y., Narabayashi, M., & Hiraoka, M. (2008). Evaluation of heterogeneity corrections in stereotactic body radiation therapy for the lung. Journal of JASTRO, 20(4), 151-154.