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Evaluation of the pediatric neuro-oncology resources available in Chile

  • Mohammad H. Abu-Arja
  • , Nicolás Rojas Del Río
  • , Andres Morales La Madrid
  • , Alvaro Lassaletta
  • , Scott L. Coven
  • , Rosa Moreno
  • , Miguel Valero
  • , Veronica Perez
  • , Felipe Espinoza
  • , Eduardo Fernandez
  • , José Santander
  • , Juan Tordecilla
  • , Veronica Oyarce
  • , Katherine Kopp
  • , Ute Bartels
  • , Ibrahim Qaddoumi
  • , Jonathan L. Finlay
  • , Adrián Cáceres
  • , Mauricio Reyes
  • , Ximena Espinoza
  • Diana S. Osorio

Research output: Contribution to journalArticlepeer-review

Abstract

PURPOSE Pediatric neuro-oncology resources are mostly unknown in Chile. We report the human and material resources available in Chilean hospitals providing pediatric neuro-oncology services. METHODS A cross-sectional survey was distributed to 17 hospitals providing pediatric neuro-oncology services (Programa Infantil Nacional de Drogas Antineoplásicas [PINDA] hospitals, 11; private, 6). RESULTS Response rate was 71% (PINDA, 8; private, 4). Pediatric neuro-oncology services were mainly provided within general hospitals (67%). Registries for pediatric CNS tumors and chemotherapy-related toxicities were available in 100% and 67% of hospitals, respectively. CNS tumors were treated by pediatric oncologists in 92% of hospitals; none were formally trained in neuro-oncology. The most used treatment protocols were the national PINDA protocols. All WHO essential medicines for childhood cancer were available in more than 80% of the hospitals except for gemcitabine, oxaliplatin, paclitaxel, and procarbazine. The median number of pediatric neurosurgeons per hospital was two (range, 2-6). General neuroradiologists were available in 83% of the centers. Pathology specimens were sent to neuropathologists (58%), adult pathologists (25%), and pediatric pathologists (17%). Intensity-modulated radiotherapy, conformal radiotherapy, and cobalt radiotherapy were used by 67%, 58%, and 42% of hospitals, respectively. Only one private hospital performed autologous hematopoietic cell transplant for children with CNS tumors. CONCLUSION A wide range of up-to-date treatment modalities are available for children with CNS tumors. Our survey highlights future directions to improve the pediatric neuro-oncology services available in Chile such as the expansion of multidisciplinary clinics, palliative care services, long-term cancer survivorship programs, dedicated clinical research support teams, establishing standardized mechanism for sending pathologic specimen for second opinion to international specialized centers, and establishing specialized neuro-oncology training program.

Original languageEnglish (US)
Pages (from-to)425-434
Number of pages10
JournalJournal of Global Oncology
Volume7
DOIs
StatePublished - 2021
Externally publishedYes

ASJC Scopus subject areas

  • General Medicine

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