Ex vivo expansion of cord blood

Ian K. McNiece; Elizabeth J. Shpall

doi:10.1007/978-1-84800-167-1_4

Ex vivo expansion of cord blood

Ian K. McNiece, Elizabeth J. Shpall

Stem Cell Transplantation

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Scopus citations

Abstract

Umbilical cord blood (CB) provides an alternate source for patients undergoing high-dose chemotherapy for treatment of cancer or genetic diseases. In particular, CB has become a standard therapeutic option for selected patients with hematologic malignancies. Several studies have reported on the use of CB for transplantation in adult patients; however, the low cell doses have limited the use of CB in this setting due to subsequent delays in engraftment. Ex vivo expansion is an approach that is being explored as a means to provide larger cell numbers from CB products.

Original language	English (US)
Title of host publication	Frontiers of Cord Blood Science
Publisher	Springer London
Pages	91-96
Number of pages	6
ISBN (Print)	9781848001664
DOIs	https://doi.org/10.1007/978-1-84800-167-1_4
State	Published - 2009

ASJC Scopus subject areas

General Medicine

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10.1007/978-1-84800-167-1_4

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AB - Umbilical cord blood (CB) provides an alternate source for patients undergoing high-dose chemotherapy for treatment of cancer or genetic diseases. In particular, CB has become a standard therapeutic option for selected patients with hematologic malignancies. Several studies have reported on the use of CB for transplantation in adult patients; however, the low cell doses have limited the use of CB in this setting due to subsequent delays in engraftment. Ex vivo expansion is an approach that is being explored as a means to provide larger cell numbers from CB products.

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Ex vivo expansion of cord blood

Abstract

ASJC Scopus subject areas

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