Fast Dixon-Based Multisequence and Multiplanar MRI for Whole-Body Detection of Cancer Metastases

Jingfei Ma, Colleen M. Costelloe, John E. Madewell, Gabriel N. Hortobagyi, Marjorie C. Green, Guang Cao, Fei Sun, Vikas Kundra

Research output: Contribution to journalArticlepeer-review

39 Scopus citations

Abstract

Purpose: To develop and demonstrate the feasibility of multisequence and multiplanar MRI for whole-body cancer detection. Materials and Methods: Two fast Dixon-based sequences and a diffusion-weighted sequence were used on a commer- cially available 1.5 T scanner for whole-body cancer detec- tion. The study enrolled 19 breast cancer patients with known metastases and in multistations acquired whole- body axial diffusion-weighted, coronal T2-weighted, axial/sagittal pre- and postcontrast T1-weighted, as well as triphasic abdomen images. Three radiologists subjectively scored Dixon images of each series for overall image quality and fat suppression uniformity on a 4-point scale (1 poor, 2 fair, 3 good, and 4 excellent). Results: Eighteen of the 19 patients completed the whole- body MRI successfully. The mean acquisition time and overall patient table time were 46 3 and 69 5 minutes, respectively. The average radiologists' scores for overall im- age quality and fat suppression uniformity were both 3.4 0.5. The image quality was consistent between patients and all completed whole-body examinations were diagnostically adequate. Conclusion: Whole-body MRI offering essentially all the most optimal tumor-imaging sequences in a typical 1-hour time slot can potentially become an appealing «one-stop- shop» for whole-body cancer imaging.

Original languageEnglish (US)
Pages (from-to)1154-1162
Number of pages9
JournalJournal of Magnetic Resonance Imaging
Volume29
Issue number5
DOIs
StatePublished - May 2009

Keywords

  • Cancer metastases
  • Fast Dixon sequences
  • Multi-sequence imaging
  • Multiplanar imaging
  • Whole-body MRI

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Fingerprint

Dive into the research topics of 'Fast Dixon-Based Multisequence and Multiplanar MRI for Whole-Body Detection of Cancer Metastases'. Together they form a unique fingerprint.

Cite this