Abstract
Purpose: To develop and demonstrate the feasibility of multisequence and multiplanar MRI for whole-body cancer detection. Materials and Methods: Two fast Dixon-based sequences and a diffusion-weighted sequence were used on a commer- cially available 1.5 T scanner for whole-body cancer detec- tion. The study enrolled 19 breast cancer patients with known metastases and in multistations acquired whole- body axial diffusion-weighted, coronal T2-weighted, axial/sagittal pre- and postcontrast T1-weighted, as well as triphasic abdomen images. Three radiologists subjectively scored Dixon images of each series for overall image quality and fat suppression uniformity on a 4-point scale (1 poor, 2 fair, 3 good, and 4 excellent). Results: Eighteen of the 19 patients completed the whole- body MRI successfully. The mean acquisition time and overall patient table time were 46 3 and 69 5 minutes, respectively. The average radiologists' scores for overall im- age quality and fat suppression uniformity were both 3.4 0.5. The image quality was consistent between patients and all completed whole-body examinations were diagnostically adequate. Conclusion: Whole-body MRI offering essentially all the most optimal tumor-imaging sequences in a typical 1-hour time slot can potentially become an appealing «one-stop- shop» for whole-body cancer imaging.
Original language | English (US) |
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Pages (from-to) | 1154-1162 |
Number of pages | 9 |
Journal | Journal of Magnetic Resonance Imaging |
Volume | 29 |
Issue number | 5 |
DOIs | |
State | Published - May 2009 |
Keywords
- Cancer metastases
- Fast Dixon sequences
- Multi-sequence imaging
- Multiplanar imaging
- Whole-body MRI
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging