FDG PET for the detection of bone metastases: Sensitivity, specificity and comparison with other imaging modalities

Colleen M. Costelloe; Hubert H. Chuang; John E. Madewell

doi:10.1016/j.cpet.2010.04.001

FDG PET for the detection of bone metastases: Sensitivity, specificity and comparison with other imaging modalities

Colleen M. Costelloe, Hubert H. Chuang, John E. Madewell

Nuclear Medicine

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

A literature review was performed of studies reporting sensitivity and specificity of [18F]fluorodeoxyglucose (FDG) PET from January 1, 2000 to January 1, 2010. PET was found to have higher sensitivity for the detection of osseous metastases when compared to CT, skeletal scintigraphy, whole body MRI and combined conventional imaging modalities. A potential exception is when comparing PET with bone scan in the setting of blastic metastases. PET may be a better indicator of active bony metastases. The efficacy of PET can be increased with fused anatomic imaging.

Original language	English (US)
Pages (from-to)	281-295
Number of pages	15
Journal	PET Clinics
Volume	5
Issue number	3
DOIs	https://doi.org/10.1016/j.cpet.2010.04.001
State	Published - Jul 2010

Keywords

Bone
FDG
Metastases
PET

ASJC Scopus subject areas

Radiation
Radiology Nuclear Medicine and imaging

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10.1016/j.cpet.2010.04.001

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abstract = "A literature review was performed of studies reporting sensitivity and specificity of [18F]fluorodeoxyglucose (FDG) PET from January 1, 2000 to January 1, 2010. PET was found to have higher sensitivity for the detection of osseous metastases when compared to CT, skeletal scintigraphy, whole body MRI and combined conventional imaging modalities. A potential exception is when comparing PET with bone scan in the setting of blastic metastases. PET may be a better indicator of active bony metastases. The efficacy of PET can be increased with fused anatomic imaging.",

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AU - Chuang, Hubert H.

AU - Madewell, John E.

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N2 - A literature review was performed of studies reporting sensitivity and specificity of [18F]fluorodeoxyglucose (FDG) PET from January 1, 2000 to January 1, 2010. PET was found to have higher sensitivity for the detection of osseous metastases when compared to CT, skeletal scintigraphy, whole body MRI and combined conventional imaging modalities. A potential exception is when comparing PET with bone scan in the setting of blastic metastases. PET may be a better indicator of active bony metastases. The efficacy of PET can be increased with fused anatomic imaging.

AB - A literature review was performed of studies reporting sensitivity and specificity of [18F]fluorodeoxyglucose (FDG) PET from January 1, 2000 to January 1, 2010. PET was found to have higher sensitivity for the detection of osseous metastases when compared to CT, skeletal scintigraphy, whole body MRI and combined conventional imaging modalities. A potential exception is when comparing PET with bone scan in the setting of blastic metastases. PET may be a better indicator of active bony metastases. The efficacy of PET can be increased with fused anatomic imaging.

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KW - Metastases

KW - PET

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FDG PET for the detection of bone metastases: Sensitivity, specificity and comparison with other imaging modalities

Abstract

Keywords

ASJC Scopus subject areas

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