@article{74755fdbd19148b1af59e9cfe7051bff,
title = "Fecal microbiota transplantation for refractory immune checkpoint inhibitor-associated colitis",
abstract = "We report the first case series of immune checkpoint inhibitors (ICI)-associated colitis successfully treated with fecal microbiota transplantation, with reconstitution of the gut microbiome and a relative increase in the proportion of regulatory T-cells within the colonic mucosa. These preliminary data provide evidence that modulation of the gut microbiome may abrogate ICI-associated colitis.",
author = "Yinghong Wang and Wiesnoski, {Diana H.} and Helmink, {Beth A.} and Vancheswaran Gopalakrishnan and Kati Choi and DuPont, {Hebert L.} and Jiang, {Zhi Dong} and Hamzah Abu-Sbeih and Sanchez, {Christopher A.} and Chang, {Chia Chi} and Parra, {Edwin R.} and Alejandro Francisco-Cruz and Raju, {Gottumukkala S.} and Stroehlein, {John R.} and Campbell, {Matthew T.} and Jianjun Gao and Subudhi, {Sumit K.} and Maru, {Dipen M.} and Blando, {Jorge M.} and Lazar, {Alexander J.} and Allison, {James P.} and Padmanee Sharma and Tetzlaff, {Michael T.} and Wargo, {Jennifer A.} and Jenq, {Robert R.}",
note = "Publisher Copyright: {\textcopyright} 2018, The Author(s), under exclusive licence to Springer Nature America, Inc.",
year = "2018",
month = dec,
day = "1",
doi = "10.1038/s41591-018-0238-9",
language = "English (US)",
volume = "24",
pages = "1804--1808",
journal = "Nature medicine",
issn = "1078-8956",
publisher = "Nature Publishing Group",
number = "12",
}