Abstract
In this issue of Blood, Deaglio and colleagues demonstrate that CD38 activates ZAP-70 and facilitates chronic lymphocytic leukemia (CLL)- cell migration toward the chemokine SDF-1 (CXCL12), suggesting that CD38 +/ZAP-70+ CLL cells have a higher propensity for homing to a supportive microenvironment.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 3820-3821 |
| Number of pages | 2 |
| Journal | Blood |
| Volume | 110 |
| Issue number | 12 |
| DOIs | |
| State | Published - Dec 1 2007 |
ASJC Scopus subject areas
- Biochemistry
- Immunology
- Hematology
- Cell Biology