Fluorescence and reflectance spectroscopy for detection of oral dysplasia and cancer

Richard A. Schwarz; Rebecca R. Richards-Kortum; Ann M. Gillenwater

doi:10.1007/978-1-4939-1758-7_26

Fluorescence and reflectance spectroscopy for detection of oral dysplasia and cancer

Richard A. Schwarz, Rebecca R. Richards-Kortum, Ann M. Gillenwater

Head & Neck Surgery

Research output: Chapter in Book/Report/Conference proceeding › Chapter

3 Scopus citations

Abstract

The development and progression of neoplasia in the oral cavity lead to measurable changes in the optical properties of oral tissue. These alterations can be detected using noninvasive optical techniques, potentially aiding in early detection and diagnosis. Various spectroscopic methods have been reported for detection of oral dysplasia and cancer. This chapter focuses on fluorescence spectroscopy, in which narrowband illumination light is used to excite endogenous fluorophores, and reflectance spectroscopy, in which broadband (white) illumination light is used to interrogate the elastic scattering properties and absorption properties of tissue.

Original language	English (US)
Title of host publication	Biomedical Optics in Otorhinolaryngology
Subtitle of host publication	Head and Neck Surgery
Publisher	Springer New York
Pages	431-449
Number of pages	19
ISBN (Electronic)	9781493917587
ISBN (Print)	9781493917570
DOIs	https://doi.org/10.1007/978-1-4939-1758-7_26
State	Published - Jan 1 2016

Keywords

Cancer
Diagnosis
Fluorescence
Reflectance
Spectroscopy

ASJC Scopus subject areas

General Medicine

Access to Document

10.1007/978-1-4939-1758-7_26

Cite this

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abstract = "The development and progression of neoplasia in the oral cavity lead to measurable changes in the optical properties of oral tissue. These alterations can be detected using noninvasive optical techniques, potentially aiding in early detection and diagnosis. Various spectroscopic methods have been reported for detection of oral dysplasia and cancer. This chapter focuses on fluorescence spectroscopy, in which narrowband illumination light is used to excite endogenous fluorophores, and reflectance spectroscopy, in which broadband (white) illumination light is used to interrogate the elastic scattering properties and absorption properties of tissue.",

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AU - Gillenwater, Ann M.

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N2 - The development and progression of neoplasia in the oral cavity lead to measurable changes in the optical properties of oral tissue. These alterations can be detected using noninvasive optical techniques, potentially aiding in early detection and diagnosis. Various spectroscopic methods have been reported for detection of oral dysplasia and cancer. This chapter focuses on fluorescence spectroscopy, in which narrowband illumination light is used to excite endogenous fluorophores, and reflectance spectroscopy, in which broadband (white) illumination light is used to interrogate the elastic scattering properties and absorption properties of tissue.

AB - The development and progression of neoplasia in the oral cavity lead to measurable changes in the optical properties of oral tissue. These alterations can be detected using noninvasive optical techniques, potentially aiding in early detection and diagnosis. Various spectroscopic methods have been reported for detection of oral dysplasia and cancer. This chapter focuses on fluorescence spectroscopy, in which narrowband illumination light is used to excite endogenous fluorophores, and reflectance spectroscopy, in which broadband (white) illumination light is used to interrogate the elastic scattering properties and absorption properties of tissue.

KW - Cancer

KW - Diagnosis

KW - Fluorescence

KW - Reflectance

KW - Spectroscopy

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BT - Biomedical Optics in Otorhinolaryngology

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ER -

Fluorescence and reflectance spectroscopy for detection of oral dysplasia and cancer

Abstract

Keywords

ASJC Scopus subject areas

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