Gallium-68 in medical imaging

Lucia Martiniova; Louis De Palatis; Elba Etchebehere; Gregory Ravizzini

doi:10.2174/1874471009666161028150654

Gallium-68 in medical imaging

Lucia Martiniova, Louis De Palatis, Elba Etchebehere, Gregory Ravizzini

Research output: Contribution to journal › Review article › peer-review

54 Scopus citations

Abstract

Over the past several years, Positron Emission Tomography (PET) imaging agents labeled with⁶⁸Gallium (⁶⁸Ga) have undergone a significant increase in clinical utilization.⁶⁸Ga is conveniently produced from a germanium-⁶⁸/gallium-⁶⁸(⁶⁸Ge/⁶⁸Ga) generator. Because of the compact size and ease of use of the generator,⁶⁸Ga labeled compounds may be more cost-effective than PET radioisotopes that are cyclotron-produced. The convenient half-life of 68Ga (T_1/2=⁶⁸min) provides sufficient radioactivity for various PET imaging applications, while delivering acceptable radiation doses to patients. This chapter summarizes the emerging clinical utilization of 68Ga-based radiotracers in medical imaging.

Original language	English (US)
Pages (from-to)	187-207
Number of pages	21
Journal	Current Radiopharmaceuticals
Volume	9
Issue number	3
DOIs	https://doi.org/10.2174/1874471009666161028150654
State	Published - Dec 1 2016

Keywords

Gallium
Generator
Neuroendocrine tumors
Positron emission tomography
PSMA
Somatostatin receptor scintigraphy

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging
Pharmacology

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10.2174/1874471009666161028150654

Cite this

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title = "Gallium-68 in medical imaging",

abstract = "Over the past several years, Positron Emission Tomography (PET) imaging agents labeled with68Gallium (68Ga) have undergone a significant increase in clinical utilization.68Ga is conveniently produced from a germanium-68/gallium-68(68Ge/68Ga) generator. Because of the compact size and ease of use of the generator,68Ga labeled compounds may be more cost-effective than PET radioisotopes that are cyclotron-produced. The convenient half-life of 68Ga (T1/2=68min) provides sufficient radioactivity for various PET imaging applications, while delivering acceptable radiation doses to patients. This chapter summarizes the emerging clinical utilization of 68Ga-based radiotracers in medical imaging.",

keywords = "Gallium, Generator, Neuroendocrine tumors, Positron emission tomography, PSMA, Somatostatin receptor scintigraphy",

author = "Lucia Martiniova and {De Palatis}, Louis and Elba Etchebehere and Gregory Ravizzini",

year = "2016",

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language = "English (US)",

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T1 - Gallium-68 in medical imaging

AU - Martiniova, Lucia

AU - De Palatis, Louis

AU - Etchebehere, Elba

AU - Ravizzini, Gregory

PY - 2016/12/1

Y1 - 2016/12/1

N2 - Over the past several years, Positron Emission Tomography (PET) imaging agents labeled with68Gallium (68Ga) have undergone a significant increase in clinical utilization.68Ga is conveniently produced from a germanium-68/gallium-68(68Ge/68Ga) generator. Because of the compact size and ease of use of the generator,68Ga labeled compounds may be more cost-effective than PET radioisotopes that are cyclotron-produced. The convenient half-life of 68Ga (T1/2=68min) provides sufficient radioactivity for various PET imaging applications, while delivering acceptable radiation doses to patients. This chapter summarizes the emerging clinical utilization of 68Ga-based radiotracers in medical imaging.

AB - Over the past several years, Positron Emission Tomography (PET) imaging agents labeled with68Gallium (68Ga) have undergone a significant increase in clinical utilization.68Ga is conveniently produced from a germanium-68/gallium-68(68Ge/68Ga) generator. Because of the compact size and ease of use of the generator,68Ga labeled compounds may be more cost-effective than PET radioisotopes that are cyclotron-produced. The convenient half-life of 68Ga (T1/2=68min) provides sufficient radioactivity for various PET imaging applications, while delivering acceptable radiation doses to patients. This chapter summarizes the emerging clinical utilization of 68Ga-based radiotracers in medical imaging.

KW - Gallium

KW - Generator

KW - Neuroendocrine tumors

KW - Positron emission tomography

KW - PSMA

KW - Somatostatin receptor scintigraphy

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Gallium-68 in medical imaging

Abstract

Keywords

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