Gastrointestinal Complications Associated with Hepatic Arterial Yttrium-90 Microsphere Therapy{A figure is presented}

Ravi Murthy; Daniel B. Brown; Riad Salem; Steven G. Meranze; Douglas M. Coldwell; Sunil Krishnan; Rodolfo Nunez; Amit Habbu; David Liu; William Ross; Alan M. Cohen; Michael Censullo

doi:10.1016/j.jvir.2007.02.002

Gastrointestinal Complications Associated with Hepatic Arterial Yttrium-90 Microsphere Therapy{A figure is presented}

Ravi Murthy, Daniel B. Brown, Riad Salem, Steven G. Meranze, Douglas M. Coldwell, Sunil Krishnan, Rodolfo Nunez, Amit Habbu, David Liu, William Ross, Alan M. Cohen, Michael Censullo

Research output: Contribution to journal › Article › peer-review

140 Scopus citations

Abstract

Hepatic arterial therapy with yttrium-90 microspheres exploits the avenue provided by the neoplastic microvasculature to deliver high-energy, low-penetrating therapeutic doses of radiation. Variant hepatic arterial anatomy, collateral vessels, and changes in flow dynamics during treatment can affect particle dispersion and lead to nontarget particle distribution and subsequent gastrointestinal morbidity. Awareness of these variances and techniques to prevent gastrointestinal tract microsphere delivery is essential in mitigating this serious complication. Our aim is to increase the understanding of the role of various imaging and preventative techniques in minimizing this undesired effect.

Original language	English (US)
Pages (from-to)	553-561
Number of pages	9
Journal	Journal of Vascular and Interventional Radiology
Volume	18
Issue number	4
DOIs	https://doi.org/10.1016/j.jvir.2007.02.002
State	Published - Apr 2007

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging
Cardiology and Cardiovascular Medicine

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Murthy, R., Brown, D. B., Salem, R., Meranze, S. G., Coldwell, D. M., Krishnan, S., Nunez, R., Habbu, A., Liu, D., Ross, W., Cohen, A. M., & Censullo, M. (2007). Gastrointestinal Complications Associated with Hepatic Arterial Yttrium-90 Microsphere Therapy{A figure is presented}. Journal of Vascular and Interventional Radiology, 18(4), 553-561. https://doi.org/10.1016/j.jvir.2007.02.002

Murthy, R, Brown, DB, Salem, R, Meranze, SG, Coldwell, DM, Krishnan, S, Nunez, R, Habbu, A, Liu, D, Ross, W, Cohen, AM & Censullo, M 2007, 'Gastrointestinal Complications Associated with Hepatic Arterial Yttrium-90 Microsphere Therapy{A figure is presented}', Journal of Vascular and Interventional Radiology, vol. 18, no. 4, pp. 553-561. https://doi.org/10.1016/j.jvir.2007.02.002

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abstract = "Hepatic arterial therapy with yttrium-90 microspheres exploits the avenue provided by the neoplastic microvasculature to deliver high-energy, low-penetrating therapeutic doses of radiation. Variant hepatic arterial anatomy, collateral vessels, and changes in flow dynamics during treatment can affect particle dispersion and lead to nontarget particle distribution and subsequent gastrointestinal morbidity. Awareness of these variances and techniques to prevent gastrointestinal tract microsphere delivery is essential in mitigating this serious complication. Our aim is to increase the understanding of the role of various imaging and preventative techniques in minimizing this undesired effect.",

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AU - Murthy, Ravi

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AU - Salem, Riad

AU - Meranze, Steven G.

AU - Coldwell, Douglas M.

AU - Krishnan, Sunil

AU - Nunez, Rodolfo

AU - Habbu, Amit

AU - Liu, David

AU - Ross, William

AU - Cohen, Alan M.

AU - Censullo, Michael

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AB - Hepatic arterial therapy with yttrium-90 microspheres exploits the avenue provided by the neoplastic microvasculature to deliver high-energy, low-penetrating therapeutic doses of radiation. Variant hepatic arterial anatomy, collateral vessels, and changes in flow dynamics during treatment can affect particle dispersion and lead to nontarget particle distribution and subsequent gastrointestinal morbidity. Awareness of these variances and techniques to prevent gastrointestinal tract microsphere delivery is essential in mitigating this serious complication. Our aim is to increase the understanding of the role of various imaging and preventative techniques in minimizing this undesired effect.

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Gastrointestinal Complications Associated with Hepatic Arterial Yttrium-90 Microsphere Therapy{A figure is presented}

Abstract

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