Abstract
Generalized morphea is associated with epoxy resin vapors and is characterized by the development of lesions shortly after exposure. Morphea presenting along with eosinophilic fasciitis (EF), or morphea/EF overlap, is rare and an indicator of poor prognosis and resistance to treatment. Here we present a case of generalized morphea/EF overlap linked to epoxy exposure. Our patient received multiple therapies—ultraviolet A1 phototherapy, prednisone, methotrexate, azathioprine, mycophenolate mofetil, cyclophosphamide, cyclosporine, and rituximab—none of which led to a significant response. The refractory nature of this disease warrants vigilance in its association with epoxy exposure.
Original language | English (US) |
---|---|
Pages (from-to) | 175-178 |
Number of pages | 4 |
Journal | JAAD Case Reports |
Volume | 4 |
Issue number | 2 |
DOIs | |
State | Published - Mar 1 2018 |
Keywords
- azathioprine
- eosinophilic fasciitis
- epoxy
- generalized morphea
- phototherapy
- ultraviolet A1
ASJC Scopus subject areas
- Dermatology