Genetic dissection of glucocorticoid receptor function in mice

François Tronche, Christoph Kellendonk, Holger M. Reichardt, Günther Schütz

Research output: Contribution to journalArticle

152 Citations (Scopus)

Abstract

Upon hormone binding, the activated glucocorticoid receptor (GR) functions as a transcription factor via different modes of action to control gene expression. Recent gene-targeting studies in mice provide new insight into the role of GR in vivo and are helping decipher the molecular mechanisms underlying its actions.

Original languageEnglish (US)
Pages (from-to)532-538
Number of pages7
JournalCurrent Opinion in Genetics and Development
Volume8
Issue number5
DOIs
StatePublished - Oct 1998

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Glucocorticoid Receptors
Dissection
Gene Targeting
Transcription Factors
Hormones
Gene Expression

ASJC Scopus subject areas

  • Genetics
  • Developmental Biology

Cite this

Genetic dissection of glucocorticoid receptor function in mice. / Tronche, François; Kellendonk, Christoph; Reichardt, Holger M.; Schütz, Günther.

In: Current Opinion in Genetics and Development, Vol. 8, No. 5, 10.1998, p. 532-538.

Research output: Contribution to journalArticle

Tronche, François ; Kellendonk, Christoph ; Reichardt, Holger M. ; Schütz, Günther. / Genetic dissection of glucocorticoid receptor function in mice. In: Current Opinion in Genetics and Development. 1998 ; Vol. 8, No. 5. pp. 532-538.
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